id | GO:0000124   Detailed information |
---|---|
  name | SAGA complex |
  namespace | cellular_component |
  def | "A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery." [PMID:10637607, PMID:17337012] |
  synonym | "Spt-Ada-Gcn5-acetyltransferase complex" EXACT [] |
  is_a | GO:0070461 ! SAGA-type complex |
  relationship | has_part GO:0071819 ! DUBm complex |
  DPGLEAN03070
  DPGLEAN07142
  DPGLEAN07704
  DPGLEAN14879
  DPGLEAN19052
  DPGLEAN21276