| id | GO:0001519 Detailed information |
|---|---|
| name | peptide amidation |
| namespace | biological_process |
| def | "The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions." [PMID:11028916] |
| subset | gosubset_prok |
| is_a | GO:0031179 ! peptide modification |