| id | GO:0002115 Detailed information
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| name | store-operated calcium entry
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| namespace | biological_process
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| def | "A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum." [GOC:hjd, PMID:11120592, PMID:17956991]
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| comment | SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum.
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| synonym | "calcium ion import" BROAD []
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| synonym | "capacitative calcium entry" EXACT []
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| synonym | "SOCE" EXACT []
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| synonym | "store-operated calcium import" EXACT []
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| is_a | GO:0006816 ! calcium ion transport
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