| id | GO:0003906 Detailed information
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| name | DNA-(apurinic or apyrimidinic site) lyase activity
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| namespace | molecular_function
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| def | "Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate." [EC:4.2.99.18]
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| subset | gosubset_prok
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| synonym | "AP endonuclease class I activity" NARROW [EC:4.2.99.18]
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| synonym | "AP lyase activity" EXACT [EC:4.2.99.18]
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| synonym | "AP site-DNA 5'-phosphomonoester-lyase activity" EXACT [EC:4.2.99.18]
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| synonym | "deoxyribonuclease (apurinic or apyrimidinic) activity" EXACT [EC:4.2.99.18]
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| synonym | "DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity" EXACT [EC:4.2.99.18]
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| synonym | "E. coli endonuclease III" RELATED [EC:4.2.99.18]
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| synonym | "E. coli endonuclease III activity" NARROW [EC:4.2.99.18]
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| synonym | "endodeoxyribonuclease (apurinic or apyrimidinic) activity" EXACT [EC:4.2.99.18]
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| synonym | "endonuclease VIII activity" RELATED []
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| synonym | "micrococcus luteus UV endonuclease" NARROW [EC:4.2.99.18]
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| synonym | "Micrococcus luteus UV endonuclease activity" NARROW [EC:4.2.99.18]
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| synonym | "Phage-T(4) UV endonuclease activity" NARROW [EC:4.2.99.18]
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| synonym | "phage-T4 UV endonuclease" BROAD [EC:4.2.99.18]
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| synonym | "Phage-T4 UV endonuclease activity" NARROW [EC:4.2.99.18]
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| synonym | "X-ray endonuclease III" RELATED [EC:4.2.99.18]
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| xref | EC:4.2.99.18
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| xref | MetaCyc:4.2.99.18-RXN
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| xref | Reactome:12450 "DNA-(apurinic or apyrimidinic site) lyase activity"
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| is_a | GO:0016835 ! carbon-oxygen lyase activity
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