| id | GO:0003917 Detailed information
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| name | DNA topoisomerase type I activity
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| namespace | molecular_function
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| def | "Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle." [PMID:8811192]
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| comment | Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
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| subset | gosubset_prok
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| synonym | "deoxyribonucleate topoisomerase" BROAD [EC:5.99.1.2]
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| synonym | "DNA topoisomerase I activity" NARROW []
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| synonym | "nicking-closing enzyme activity" RELATED [EC:5.99.1.2]
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| synonym | "omega-protein activity" RELATED [EC:5.99.1.2]
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| synonym | "relaxing enzyme activity" RELATED [EC:5.99.1.2]
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| synonym | "swivelase activity" RELATED [EC:5.99.1.2]
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| synonym | "topoisomerase" BROAD [EC:5.99.1.2]
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| synonym | "type I DNA topoisomerase activity" EXACT []
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| synonym | "type I topoisomerase activity" EXACT []
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| synonym | "untwisting enzyme activity" RELATED [EC:5.99.1.2]
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| xref | EC:5.99.1.2
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| xref | MetaCyc:5.99.1.2-RXN
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| is_a | GO:0003916 ! DNA topoisomerase activity
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