id | GO:0003918   Detailed information |
---|---|
  name | DNA topoisomerase (ATP-hydrolyzing) activity |
  namespace | molecular_function |
  def | "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192] |
  subset | gosubset_prok |
  synonym | "deoxyribonucleate topoisomerase" BROAD [EC:5.99.1.3] |
  synonym | "deoxyribonucleic topoisomerase activity" EXACT [EC:5.99.1.3] |
  synonym | "DNA gyrase activity" EXACT [] |
  synonym | "DNA topoisomerase (ATP-hydrolysing)" BROAD [EC:5.99.1.3] |
  synonym | "DNA topoisomerase II" RELATED [EC:5.99.1.3] |
  synonym | "DNA topoisomerase IV activity" EXACT [] |
  synonym | "DNA topoisomerase type II activity" EXACT [] |
  synonym | "DNA-gyrase activity" EXACT [EC:5.99.1.3] |
  synonym | "topoisomerase" BROAD [EC:5.99.1.3] |
  synonym | "topoisomerase II" EXACT [] |
  synonym | "type II DNA topoisomerase activity" EXACT [EC:5.99.1.3] |
  xref | EC:5.99.1.3 |
  xref | MetaCyc:5.99.1.3-RXN |
  xref | Wikipedia:Type_II_topoisomerase |
  is_a | GO:0003916 ! DNA topoisomerase activity |
  DPGLEAN04878
  DPGLEAN21005