id | GO:0004420   Detailed information |
---|---|
  name | hydroxymethylglutaryl-CoA reductase (NADPH) activity |
  namespace | molecular_function |
  def | "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH." [EC:1.1.1.34, RHEA:15992] |
  subset | gosubset_prok |
  synonym | "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity" BROAD [EC:1.1.1.34] |
  synonym | "HMG-CoA reductase activity" BROAD [EC:1.1.1.34] |
  xref | EC:1.1.1.34 |
  xref | KEGG:R02082 |
  xref | MetaCyc:1.1.1.34-RXN |
  xref | Reactome:11408 "hydroxymethylglutaryl-CoA reductase (NADPH) activity" |
  xref | RHEA:15992 |
  is_a | GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
  DPGLEAN22610