id | GO:0004512   Detailed information |
---|---|
  name | inositol-3-phosphate synthase activity |
  namespace | molecular_function |
  def | "Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form." [EC:5.5.1.4, RHEA:10719] |
  subset | gosubset_prok |
  synonym | "1L-myo-inositol-1-phosphate lyase (isomerizing)" EXACT [EC:5.5.1.4] |
  synonym | "D-glucose 6-phosphate cycloaldolase activity" EXACT [EC:5.5.1.4] |
  synonym | "glucocycloaldolase activity" EXACT [EC:5.5.1.4] |
  synonym | "glucose 6-phosphate cyclase activity" EXACT [EC:5.5.1.4] |
  synonym | "glucose-6-phosphate inositol monophosphate cycloaldolase activity" EXACT [EC:5.5.1.4] |
  synonym | "inositol 1-phosphate synthatase activity" EXACT [EC:5.5.1.4] |
  synonym | "inositol 1-phosphate synthetase activity" EXACT [EC:5.5.1.4] |
  synonym | "myo-inositol-1-phosphate synthase activity" EXACT [] |
  xref | EC:5.5.1.4 |
  xref | KEGG:R07324 |
  xref | MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN |
  xref | Reactome:12283 "inositol-3-phosphate synthase activity" |
  xref | RHEA:10719 |
  is_a | GO:0016872 ! intramolecular lyase activity |
  DPGLEAN01215
  DPGLEAN16478