| id | GO:0004663 Detailed information
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| name | Rab geranylgeranyltransferase activity
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| namespace | molecular_function
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| def | "Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family." [EC:2.5.1.60, GOC:mah, PMID:8621375]
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| synonym | "geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity" EXACT []
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| synonym | "GGTase-II activity" EXACT []
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| synonym | "GGTaseII activity" EXACT []
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| synonym | "protein geranylgeranyltransferase type II activity" EXACT []
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| synonym | "Rab-protein geranylgeranyltransferase activity" EXACT []
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| synonym | "RabGGTase activity" EXACT []
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| synonym | "type II protein geranyl-geranyltransferase activity" EXACT [EC:2.5.1.60]
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| xref | EC:2.5.1.60
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| xref | MetaCyc:2.5.1.60-RXN
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| xref | MetaCyc:RXN-3701
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| is_a | GO:0004661 ! protein geranylgeranyltransferase activity
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