| id | GO:0004707 Detailed information
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| name | MAP kinase activity
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| namespace | molecular_function
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| alt_id | GO:0008338
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| alt_id | GO:0008339
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| alt_id | GO:0016908
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| def | "Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli." [GOC:ma, ISBN:0198547684]
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| synonym | "ATP:protein phosphotransferase (MAPKK-activated) activity" EXACT [EC:2.7.11.24]
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| synonym | "Dp38" RELATED [EC:2.7.11.24]
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| synonym | "ERK" RELATED [EC:2.7.11.24]
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| synonym | "ERK1" EXACT []
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| synonym | "ERK2" RELATED []
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| synonym | "extracellular signal-regulated kinase activity" NARROW [EC:2.7.11.24]
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| synonym | "LeMPK3" RELATED [EC:2.7.11.24]
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| synonym | "MAP kinase 1 activity" NARROW []
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| synonym | "MAP kinase 2 activity" NARROW []
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| synonym | "MAP-2 kinase activity" NARROW [EC:2.7.11.24]
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| synonym | "MAPK" RELATED [EC:2.7.11.24]
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| synonym | "MBP kinase I activity" NARROW [EC:2.7.11.24]
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| synonym | "MBP kinase II activity" NARROW [EC:2.7.11.24]
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| synonym | "mitogen activated kinase activity" EXACT []
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| synonym | "mitogen-activated protein kinase activity" EXACT [EC:2.7.11.24]
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| synonym | "MP kinase activity" NARROW []
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| synonym | "Mpk2" NARROW []
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| synonym | "myelin basic protein kinase activity" NARROW [EC:2.7.11.24]
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| synonym | "p38" NARROW []
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| synonym | "p38-2" RELATED [EC:2.7.11.24]
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| synonym | "p38delta" RELATED [EC:2.7.11.24]
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| synonym | "p42 mitogen-activated protein kinase activity" NARROW [EC:2.7.11.24]
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| synonym | "p42mapk" RELATED [EC:2.7.11.24]
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| synonym | "p44mpk" RELATED [EC:2.7.11.24]
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| synonym | "PMK-1" RELATED [EC:2.7.11.24]
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| synonym | "PMK-2" RELATED [EC:2.7.11.24]
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| synonym | "PMK-3" RELATED [EC:2.7.11.24]
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| synonym | "pp42" RELATED [EC:2.7.11.24]
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| synonym | "pp44mapk" RELATED [EC:2.7.11.24]
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| synonym | "SAPK2" NARROW []
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| synonym | "STK26" RELATED [EC:2.7.11.24]
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| xref | EC:2.7.11.24
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| xref | KEGG:R00162
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| xref | MetaCyc:2.7.11.24-RXN
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| xref | Reactome:4049 "MAP kinase activity"
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| is_a | GO:0004702 ! receptor signaling protein serine/threonine kinase activity
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