| id | GO:0004708 Detailed information
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| name | MAP kinase kinase activity
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| namespace | molecular_function
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| def | "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in MAP kinases. It is a dual-specificity mitogen-activated protein kinase kinase and requires activation by the serine/threonine kinase, MAP kinase kinase kinase." [ISBN:0198547684]
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| synonym | "ATP:protein phosphotransferase (MAPKKK-activated) activity" EXACT [EC:2.7.12.2]
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| synonym | "ERK activator kinase activity" EXACT []
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| synonym | "MAP kinase kinase 4 activity" NARROW [EC:2.7.12.2]
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| synonym | "MAP kinase kinase 7 activity" NARROW [EC:2.7.12.2]
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| synonym | "MAP kinase or ERK kinase activity" RELATED [EC:2.7.12.2]
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| synonym | "MAP2K" RELATED [EC:2.7.12.2]
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| synonym | "MAPKK" RELATED [EC:2.7.12.2]
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| synonym | "MAPKK activity" EXACT []
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| synonym | "MAPKK1" RELATED [EC:2.7.12.2]
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| synonym | "MEK activity" BROAD []
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| synonym | "MEK1" RELATED [EC:2.7.12.2]
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| synonym | "MEK2" RELATED [EC:2.7.12.2]
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| synonym | "mitogen-activated protein kinase kinase activity" EXACT [EC:2.7.12.2]
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| synonym | "MKK" RELATED [EC:2.7.12.2]
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| synonym | "MKK2" RELATED [EC:2.7.12.2]
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| synonym | "MKK4" RELATED [EC:2.7.12.2]
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| synonym | "MKK6" RELATED [EC:2.7.12.2]
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| synonym | "MKK7" RELATED [EC:2.7.12.2]
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| synonym | "STK27" RELATED [EC:2.7.12.2]
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| xref | EC:2.7.11.-
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| xref | MetaCyc:2.7.12.2-RXN
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| xref | Reactome:14146 "MAP kinase kinase activity"
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| is_a | GO:0004712 ! protein serine/threonine/tyrosine kinase activity
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