| id | GO:0005085 Detailed information
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| name | guanyl-nucleotide exchange factor activity
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| namespace | molecular_function
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| alt_id | GO:0008433
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| alt_id | GO:0016219
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| alt_id | GO:0019839
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| def | "Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:kd, GOC:mah]
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| subset | gosubset_prok
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| synonym | "GDP-dissociation stimulator activity" EXACT []
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| synonym | "GDS" EXACT []
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| synonym | "GEF" EXACT []
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| synonym | "GNRP" NARROW []
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| synonym | "guanyl-nucleotide release factor activity" EXACT []
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| synonym | "guanyl-nucleotide releasing factor" EXACT []
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| xref | Reactome:11431 "guanyl-nucleotide exchange factor activity"
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| is_a | GO:0030695 ! GTPase regulator activity
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| relationship | negatively_regulates GO:0019003 ! GDP binding
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