id | GO:0005242   Detailed information |
---|---|
  name | inward rectifier potassium channel activity |
  namespace | molecular_function |
  def | "Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself." [GOC:cb, GOC:mah, PMID:14977398] |
  subset | gosubset_prok |
  synonym | "Kir channel activity" EXACT [GOC:cb] |
  is_a | GO:0005249 ! voltage-gated potassium channel activity |
  is_a | GO:0015276 ! ligand-gated ion channel activity |
  DPGLEAN03160
  DPGLEAN06488
  DPGLEAN07413
  DPGLEAN08940
  DPGLEAN14737
  DPGLEAN14935
  DPGLEAN16676
  DPGLEAN17348
  DPGLEAN17749
  DPGLEAN17752