| id | GO:0006099 Detailed information
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| name | tricarboxylic acid cycle
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| namespace | biological_process
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| def | "A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
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| subset | gosubset_prok
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| synonym | "citric acid cycle" EXACT []
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| synonym | "Krebs cycle" EXACT []
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| synonym | "TCA cycle" EXACT []
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| xref | MetaCyc:P105-PWY
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| xref | MetaCyc:P42-PWY
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| xref | MetaCyc:TCA
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| xref | Reactome:1252945 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1279879 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1298791 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1326448 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1352564 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1372791 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1392801 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1417278 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1450367 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1470904 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1482937 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1496727 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1514117 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1520939 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1526692 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1532421 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1535974 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1537983 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1539234 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:1540292 "Citric acid cycle (TCA cycle)"
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| xref | Reactome:71403 "Citric acid cycle (TCA cycle)"
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| xref | Wikipedia:Tricarboxylic_acid_cycle
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| is_a | GO:0046356 ! acetyl-CoA catabolic process
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| relationship | part_of GO:0009060 ! aerobic respiration
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