id | GO:0006621   Detailed information |
---|---|
  name | protein retention in ER lumen |
  namespace | biological_process |
  def | "The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER." [ISBN:0716731363, PMID:12972550] |
  synonym | "maintenance of protein location in ER lumen" BROAD [GOC:dph, GOC:tb] |
  is_a | GO:0035437 ! maintenance of protein localization in endoplasmic reticulum |
  DPGLEAN00605
  DPGLEAN13336