id | GO:0006915   Detailed information |
---|---|
  name | apoptosis |
  namespace | biological_process |
  alt_id | GO:0008632 |
  def | "A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell." [GOC:go_curators, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", PMID:18846107] |
  synonym | "apoptotic cell death" EXACT [GOC:sl] |
  synonym | "apoptotic program" NARROW [GOC:add] |
  synonym | "apoptotic programmed cell death" EXACT [] |
  synonym | "programmed cell death by apoptosis" EXACT [] |
  synonym | "signaling (initiator) caspase activity" RELATED [] |
  synonym | "type I programmed cell death" NARROW [] |
  xref | Reactome:109581 "Apoptosis" |
  xref | Reactome:1252953 "Apoptosis" |
  xref | Reactome:1253485 "NADE modulates death signalling" |
  xref | Reactome:1253487 "NRAGE signals death through JNK" |
  xref | Reactome:1253559 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1279984 "Apoptosis" |
  xref | Reactome:1280422 "NADE modulates death signalling" |
  xref | Reactome:1280424 "NRAGE signals death through JNK" |
  xref | Reactome:1280425 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1298877 "Apoptosis" |
  xref | Reactome:1299256 "NADE modulates death signalling" |
  xref | Reactome:1299258 "NRAGE signals death through JNK" |
  xref | Reactome:1299325 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1326456 "Apoptosis" |
  xref | Reactome:1327001 "NADE modulates death signalling" |
  xref | Reactome:1327003 "NRAGE signals death through JNK" |
  xref | Reactome:1327004 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1352572 "Apoptosis" |
  xref | Reactome:1353095 "NADE modulates death signalling" |
  xref | Reactome:1353097 "NRAGE signals death through JNK" |
  xref | Reactome:1353098 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1372799 "Apoptosis" |
  xref | Reactome:1373284 "NRAGE signals death through JNK" |
  xref | Reactome:1373286 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1392809 "Apoptosis" |
  xref | Reactome:1393299 "NRAGE signals death through JNK" |
  xref | Reactome:1393372 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1417383 "Apoptosis" |
  xref | Reactome:1417797 "NRAGE signals death through JNK" |
  xref | Reactome:1417869 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1450375 "Apoptosis" |
  xref | Reactome:1450896 "NRAGE signals death through JNK" |
  xref | Reactome:1450958 "NRIF signals cell death from the nucleus" |
  xref | Reactome:1471339 "NRAGE signals death through JNK" |
  xref | Reactome:1471362 "Apoptosis" |
  xref | Reactome:1483249 "NRAGE signals death through JNK" |
  xref | Reactome:1483323 "Apoptosis" |
  xref | Reactome:1496989 "NRAGE signals death through JNK" |
  xref | Reactome:1497027 "Apoptosis" |
  xref | Reactome:1514376 "NRAGE signals death through JNK" |
  xref | Reactome:1514414 "Apoptosis" |
  xref | Reactome:1521264 "Apoptosis" |
  xref | Reactome:1526930 "NRAGE signals death through JNK" |
  xref | Reactome:1526973 "Apoptosis" |
  xref | Reactome:1532666 "NRAGE signals death through JNK" |
  xref | Reactome:1532709 "Apoptosis" |
  xref | Reactome:1536054 "Apoptosis" |
  xref | Reactome:193648 "NRAGE signals death through JNK" |
  xref | Reactome:205025 "NADE modulates death signalling" |
  xref | Reactome:205043 "NRIF signals cell death from the nucleus" |
  xref | Wikipedia:Apoptosis |
  is_a | GO:0012501 ! programmed cell death |
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