| id | GO:0006956 Detailed information
|
|---|
| name | complement activation
|
|---|
| namespace | biological_process
|
|---|
| def | "Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway." [GO_REF:0000022, GOC:add, GOC:mtg_15nov05, ISBN:0781735149 "Fundamental Immunology"]
|
|---|
| comment | This term was improved by GO_REF:0000022. It was moved.
|
|---|
| synonym | "complement activity" RELATED []
|
|---|
| synonym | "complement cascade" EXACT [GOC:add]
|
|---|
| synonym | "complement response" EXACT []
|
|---|
| xref | Reactome:1253355 "Initial triggering of complement"
|
|---|
| xref | Reactome:1253357 "Activation of C3 and C5"
|
|---|
| xref | Reactome:1280295 "Initial triggering of complement"
|
|---|
| xref | Reactome:1280297 "Activation of C3 and C5"
|
|---|
| xref | Reactome:1299146 "Initial triggering of complement"
|
|---|
| xref | Reactome:1299148 "Activation of C3 and C5"
|
|---|
| xref | Reactome:1326873 "Initial triggering of complement"
|
|---|
| xref | Reactome:1326875 "Activation of C3 and C5"
|
|---|
| xref | Reactome:1352965 "Initial triggering of complement"
|
|---|
| xref | Reactome:1373167 "Initial triggering of complement"
|
|---|
| xref | Reactome:1393205 "Initial triggering of complement"
|
|---|
| xref | Reactome:1417669 "Initial triggering of complement"
|
|---|
| xref | Reactome:1417671 "Activation of C3 and C5"
|
|---|
| xref | Reactome:1450771 "Initial triggering of complement"
|
|---|
| xref | Reactome:1450773 "Activation of C3 and C5"
|
|---|
| xref | Reactome:166663 "Initial triggering of complement"
|
|---|
| xref | Reactome:174577 "Activation of C3 and C5"
|
|---|
| is_a | GO:0002252 ! immune effector process
|
|---|
| is_a | GO:0002253 ! activation of immune response
|
|---|
| is_a | GO:0006959 ! humoral immune response
|
|---|
| is_a | GO:0072376 ! protein activation cascade
|
|---|