id | GO:0007228   Detailed information |
---|---|
  name | positive regulation of hh target transcription factor activity |
  namespace | biological_process |
  def | "Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited." [GOC:dph, GOC:tb, PMID:11912487, PMID:15057936] |
  synonym | "activation of hh target transcription factor" EXACT [GOC:dph, GOC:tb] |
  synonym | "positive regulation of hedgehog target transcription factor" EXACT [GOC:bf, GOC:ecd] |
  is_a | GO:0051091 ! positive regulation of sequence-specific DNA binding transcription factor activity |
  relationship | part_of GO:0007227 ! signal transduction downstream of smoothened |
  DPGLEAN04138
  DPGLEAN07088
  DPGLEAN09330
  DPGLEAN16418