| id | GO:0007254 Detailed information
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| name | JNK cascade
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| namespace | biological_process
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| def | "A cascade of protein kinase activities, culminating in the phosphorylation and activation of a member of the JUN kinase subfamily of stress-activated protein kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress." [GOC:bf, PMID:11790549]
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| synonym | "JNK1 cascade" NARROW [GOC:add]
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| synonym | "JNK2 cascade" NARROW [GOC:add]
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| synonym | "JNK3 cascade" NARROW [GOC:add]
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| synonym | "MAPK10 cascade" NARROW [GOC:add]
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| synonym | "MAPK8 cascade" NARROW [GOC:add]
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| synonym | "MAPK9 cascade" NARROW [GOC:add]
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| synonym | "SAPK cascade" BROAD []
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| synonym | "stress-activated protein kinase cascade" BROAD []
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| xref | Reactome:1253365 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1280305 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1299157 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1326883 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1352975 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1373172 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1393183 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1417675 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1450781 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1483199 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1526902 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:1532635 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| xref | Reactome:450321 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
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| is_a | GO:0000165 ! MAPKKK cascade
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| is_a | GO:0031098 ! stress-activated protein kinase signaling cascade
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