id | GO:0008622   Detailed information |
---|---|
  name | epsilon DNA polymerase complex |
  namespace | cellular_component |
  def | "A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair." [PMID:15814431, PMID:9745046] |
  synonym | "DNA polymerase epsilon complex" EXACT [CORUM:420] |
  is_a | GO:0042575 ! DNA polymerase complex |
  is_a | GO:0044454 ! nuclear chromosome part |
  relationship | part_of GO:0000109 ! nucleotide-excision repair complex |
  relationship | part_of GO:0043601 ! nuclear replisome |
  DPGLEAN00715
  DPGLEAN12216
  DPGLEAN12477
  DPGLEAN20299