| id | GO:0016442 Detailed information |
|---|---|
| name | RNA-induced silencing complex |
| namespace | cellular_component |
| def | "A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation." [PMID:10749213, PMID:15145345] |
| synonym | "RISC complex" EXACT [] |
| xref | Wikipedia:RNA-induced_silencing_complex |
| is_a | GO:0031332 ! RNAi effector complex |