id | GO:0016513   Detailed information |
---|---|
  name | core-binding factor complex |
  namespace | cellular_component |
  def | "A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit." [PMID:15156179, PMID:8497254] |
  synonym | "AML1 complex" NARROW [] |
  synonym | "CBF complex" EXACT [] |
  synonym | "PEPB2 complex" NARROW [] |
  is_a | GO:0005667 ! transcription factor complex |
  DPGLEAN04490