id | GO:0016564   Detailed information |
---|---|
  name | transcription repressor activity |
  namespace | molecular_function |
  def | "OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription." [GOC:mah] |
  comment | This term was obsoleted because it is essentially identical to a Process term, i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function. |
  subset | gosubset_prok |
  synonym | "negative transcriptional regulator activity" EXACT [] |
  synonym | "transcriptional repressor activity" EXACT [] |
  is_obsolete | true |
  consider | GO:0000988 |
  consider | GO:0001071 |
  consider | GO:0045892 |
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