id | GO:0016580   Detailed information |
---|---|
  name | Sin3 complex |
  namespace | cellular_component |
  def | "A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins." [PMID:10589671, PMID:11743021, PMID:12865422] |
  is_a | GO:0070822 ! Sin3-type complex |
  DPGLEAN01608
  DPGLEAN05175
  DPGLEAN14740
  DPGLEAN18689
  DPGLEAN19432
  DPGLEAN22611