| id | GO:0016581 Detailed information |
|---|---|
| name | NuRD complex |
| namespace | cellular_component |
| def | "An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins." [PMID:10589671, PMID:11743021, PMID:17289569] |
| synonym | "Mi-2 complex" EXACT [] |
| synonym | "NRD complex" EXACT [] |
| synonym | "nucleosome remodeling and histone deacetylation complex" EXACT [] |
| is_a | GO:0000118 ! histone deacetylase complex |
| is_a | GO:0017053 ! transcriptional repressor complex |