id | GO:0019005   Detailed information |
---|---|
  name | SCF ubiquitin ligase complex |
  namespace | cellular_component |
  def | "A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063] |
  synonym | "CDL1 complex" EXACT [] |
  synonym | "CRL1 complex" EXACT [] |
  synonym | "Cul1-RING ubiquitin ligase complex" EXACT [] |
  synonym | "cullin-RING ligase 1" EXACT [] |
  synonym | "SCF complex" EXACT [] |
  synonym | "SCF complex substrate recognition subunit" NARROW [] |
  synonym | "Skp1/Cul1/F-box protein complex" EXACT [] |
  xref | Wikipedia:SCF_complex |
  is_a | GO:0031461 ! cullin-RING ubiquitin ligase complex |
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