id | GO:0030057   Detailed information |
---|---|
  name | desmosome |
  namespace | cellular_component |
  def | "A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism." [GOC:mah, GOC:mtg_muscle, ISBN:0815332181] |
  synonym | "macula adherens" EXACT [] |
  synonym | "spot desmosome" EXACT [] |
  xref | Wikipedia:Desmosome |
  is_a | GO:0005911 ! cell-cell junction |
  is_a | GO:0070161 ! anchoring junction |
  DPGLEAN09728
  DPGLEAN10840