id | GO:0030122   Detailed information |
---|---|
  name | AP-2 adaptor complex |
  namespace | cellular_component |
  def | "A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle; vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC)." [GOC:mah, PMID:10611976, PMID:21097499] |
  synonym | "HA2" EXACT [] |
  synonym | "HA2 clathrin adaptor" EXACT [] |
  is_a | GO:0030131 ! clathrin adaptor complex |
  is_a | GO:0044433 ! cytoplasmic vesicle part |
  is_a | GO:0044459 ! plasma membrane part |
  relationship | part_of GO:0030128 ! clathrin coat of endocytic vesicle |
  relationship | part_of GO:0030132 ! clathrin coat of coated pit |
  DPGLEAN14189