id | GO:0033596   Detailed information |
---|---|
  name | TSC1-TSC2 complex |
  namespace | cellular_component |
  def | "A heterodimeric protein complex consisting of tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway." [PMID:10585443, PMID:17121544, PMID:9580671] |
  synonym | "tuberin-hamartin complex " EXACT [] |
  synonym | "tuberous sclerosis complex" EXACT [] |
  is_a | GO:0043234 ! protein complex |
  is_a | GO:0044445 ! cytosolic part |
  DPGLEAN12791