| id | GO:0035004 Detailed information
|
|---|
| name | phosphatidylinositol 3-kinase activity
|
|---|
| namespace | molecular_function
|
|---|
| def | "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring to generate the 3-phosphoinositides: phosphatidylinositol-3-phosphate [PI(3)P], phosphatidylinositol-3,4-bisphosphate [PI(3,4)P2] and phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3]." [GOC:bf, PMID:10209156, PMID:9255069]
|
|---|
| synonym | "phosphoinositide 3-kinase activity" EXACT [GOC:curators]
|
|---|
| xref | EC:2.7.1.-
|
|---|
| xref | Wikipedia:Phosphoinositide_3-kinase
|
|---|
| is_a | GO:0001727 ! lipid kinase activity
|
|---|
| is_a | GO:0004428 ! inositol or phosphatidylinositol kinase activity
|
|---|
| is_a | GO:0016773 ! phosphotransferase activity, alcohol group as acceptor
|
|---|
| relationship | part_of GO:0046854 ! phosphatidylinositol phosphorylation
|
|---|