| id | GO:0035098 Detailed information |
|---|---|
| name | ESC/E(Z) complex |
| namespace | cellular_component |
| def | "A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4." [GOC:bf, GOC:sp, PMID:12408863, PMID:12408864, PMID:20064375] |
| synonym | "Extra Sex Combs/Enhancer of Zeste complex" EXACT [] |
| synonym | "PRC2 complex" EXACT [GOC:sp, PMID:20064375] |
| is_a | GO:0031519 ! PcG protein complex |
| is_a | GO:0035097 ! histone methyltransferase complex |