id | GO:0035103   Detailed information |
---|---|
  name | sterol regulatory element binding protein cleavage |
  namespace | biological_process |
  def | "The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus and upregulate transcription of target genes, in response to altered levels of one or more lipids." [GOC:bf, PMID:12923525] |
  synonym | "SREBP cleavage" EXACT [] |
  is_a | GO:0044267 ! cellular protein metabolic process |
  is_a | GO:0051605 ! protein maturation by peptide bond cleavage |
  relationship | part_of GO:0032933 ! SREBP-mediated signaling pathway |
  DPGLEAN00015
  DPGLEAN08823
  DPGLEAN09988
  DPGLEAN19382