id | GO:0035195   Detailed information |
---|---|
  name | gene silencing by miRNA |
  namespace | biological_process |
  def | "Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression." [PMID:14744438, PMID:15066275, PMID:15066283] |
  synonym | "gene silencing by microRNA" EXACT [GOC:pr] |
  synonym | "microRNA-mediated gene silencing" EXACT [] |
  synonym | "miRNA-mediated gene silencing" EXACT [GOC:dph, GOC:tb] |
  is_a | GO:0035194 ! posttranscriptional gene silencing by RNA |
  DPGLEAN02629
  DPGLEAN04364
  DPGLEAN04775
  DPGLEAN07691
  DPGLEAN08117
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