id | GO:0045063   Detailed information
|
---|
  name | T-helper 1 cell differentiation
|
---|
  namespace | biological_process
|
---|
  def | "The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma." [CL:0000545, GOC:ebc]
|
---|
  comment | Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
|
---|
  synonym | "T-helper 1 cell development" RELATED [GOC:add]
|
---|
  is_a | GO:0042093 ! T-helper cell differentiation
|
---|
  relationship | part_of GO:0042088 ! T-helper 1 type immune response
|
---|