id | GO:0051864   Detailed information |
---|---|
  name | histone demethylase activity (H3-K36 specific) |
  namespace | molecular_function |
  def | "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein." [PMID:16362057] |
  synonym | "[histone-H3]-lysine-36 demethylase activity" EXACT [] |
  synonym | "H3-K36-specific demethylase activity" EXACT [EC:1.14.11.27] |
  synonym | "histone H3-lysine-36 demethylase activity" EXACT [EC:1.14.11.27] |
  synonym | "histone-lysine (H3-K36) demethylase activity" EXACT [EC:1.14.11.27] |
  synonym | "histone-lysine demethylase activity (H3-K36 specific)" EXACT [] |
  synonym | "histone-lysine(H3-K36) demethylase activity" EXACT [] |
  synonym | "JHDM1A activity" NARROW [EC:1.14.11.27] |
  synonym | "JmjC domain-containing histone demethylase 1A activity" NARROW [EC:1.14.11.27] |
  synonym | "protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.27] |
  synonym | "protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity" EXACT [EC:1.14.11.27] |
  xref | EC:1.14.11.27 |
  xref | MetaCyc:RXN-8660 |
  xref | MetaCyc:RXN-8661 |
  is_a | GO:0016706 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors |
  is_a | GO:0032452 ! histone demethylase activity |
  relationship | part_of GO:0070544 ! histone H3-K36 demethylation |
  DPGLEAN06931
  DPGLEAN12815
  DPGLEAN16037
  DPGLEAN18276