id | GO:0070513   Detailed information |
---|---|
  name | death domain binding |
  namespace | molecular_function |
  def | "Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB." [GOC:BHF, GOC:rl, InterPro:IPR000488, Pfam:PF00531] |
  comment | For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'. |
  is_a | GO:0019904 ! protein domain specific binding |
  DPGLEAN16618