| New model in OGS2.0 | DPOGS215534 |
|---|---|
| Genomic Position | scaffold860:- 149-4327 |
| See gene structure | |
| CDS Length | 2064 |
| Paired RNAseq reads | 252 |
| Single RNAseq reads | 751 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA012027 (8e-21) |
| Best Drosophila hit | Mlh1 (5e-48) |
| Best Human hit | DNA mismatch repair protein Mlh1 isoform 1 (2e-46) |
| Best NR hit (blastp) | mutL homolog 1 [Nasonia vitripennis] (1e-67) |
| Best NR hit (blastx) | mutL homolog 1 [Nasonia vitripennis] (3e-55) |
| GeneOntology terms | GO:0005634 nucleus GO:0007049 cell cycle GO:0005524 ATP binding GO:0005694 chromosome GO:0006974 response to DNA damage stimulus GO:0007060 male meiosis chromosome segregation GO:0007126 meiosis GO:0007283 spermatogenesis GO:0005712 chiasma GO:0030983 mismatched DNA binding GO:0016447 somatic recombination of immunoglobulin gene segments GO:0001673 male germ cell nucleus GO:0000795 synaptonemal complex GO:0000794 condensed nuclear chromosome GO:0006303 double-strand break repair via nonhomologous end joining GO:0007131 reciprocal meiotic recombination GO:0006298 mismatch repair GO:0016446 somatic hypermutation of immunoglobulin genes GO:0045190 isotype switching GO:0045132 meiotic chromosome segregation GO:0000712 resolution of meiotic recombination intermediates GO:0006281 DNA repair GO:0007140 male meiosis GO:0008630 DNA damage response, signal transduction resulting in induction of apoptosis GO:0045950 negative regulation of mitotic recombination GO:0000793 condensed chromosome GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening GO:0048477 oogenesis GO:0000239 pachytene GO:0043060 meiotic metaphase I plate congression GO:0032389 MutLalpha complex GO:0032137 guanine/thymine mispair binding GO:0043566 structure-specific DNA binding GO:0002204 somatic recombination of immunoglobulin genes involved in immune response GO:0051257 spindle midzone assembly involved in meiosis |
| InterPro families | IPR014762 DNA mismatch repair, conserved site IPR003594 ATPase-like, ATP-binding domain IPR011186 DNA mismatch repair protein Mlh1 IPR002099 DNA mismatch repair protein |
| Orthology group | MCL13190 |
Nucleotide sequence:
ATGTGCGAACCAGGAATAATACGAAAACTTGACGAAGAAGTAGTAAATCGTATCGCTGCC
GGTGAAATAGTACAACGACCAGCAAATGCTTTAAAAGAACTGATAGAAAATAGTTTAGAT
GCCCATTCTAATAATATAATAATAACAGTAAAAGCCGGTGGCTTGAAGTATCTACAGATT
CAAGACAATGGCACAGGAATTCGCAGTGACAACTTAGACATAGTCTGTGAGAGATTCACT
ACATCTAAATTAAAGCAATATGAAGATTTACAAGCTATTAGTACTTATGGATTCCGCGGA
GAGGCTTTGGCCAGCATCAGTCATATTGCCCATTTGACTATACTTACAAAGACTGCTAAT
GAGAAATGTGCTTATAACGAGGAGTTATTCTACGAAACCATTCTCTATGATTTCCAAAAT
CTCGGTTTAATTAAATTATCGAATCCGTTGCCCTTAGAGGAACTGTTGGTACTAGGACTC
GGTTCGCACGAAGAGGAATGGGACAACGACTTAGGTGACATGACAGAAATGGCTGCACAG
ATGACAAAATTACTCATAAGCAAAGGTCCTATGTTATATGAATATTTTTCGATGGAAATT
AACAACAAAGGCGAGTTATTGTCTCTGCCTTTGCTATTGGACGGTCACACCCCCTTCATG
GGAGCATTGCCAGTGTACTTAGTTAGACTAGTAACTGAAGTGAACTGGGAGTCGGAGAAG
GAGTGTTTCGATACGTTCAGCCGACAGACAGCTATATTTTATTCACAACCAAACAGAGAT
TCACAGGAAGACGTCTCCGAGACCGAGTCCTGGAAACAGGAGCACATAATATTTCCAGCT
ATAAGAAGGAATTTCTTGCCGCCTAGCAGTTTCGTCAGCAACGGATCTATACTACAAATA
GCTAATTTATGCGACCTCTATAAAGCTCGCCTGCCAGGTGCGACTATGGTCGAGGAAATC
ATCAAAAAGACAACAGACGGTGCAAAAGTATACGCAAAAGATTTAGTACGAGTGGATTCG
GATGCTCAGAAAATTGATAAATTCTTCAAAGTAACTACAATAGATAGGTCAAAAGAAAAC
GAAACAAATGAAACAAGAAATGAGACAACGAATCAAGATAGTAAGGAAAGAAATGAAGGG
ACAGAAGCCGTTGAAGTTATTGATAATAACGAAGTTATTGATGAAACAGATGATATAATT
AATAATTCTCTTGTATCGGAACCAAATGAGACGAAGGCAAAGAAATATAAAACAGCTATC
AGTAGCAACGTCACATACATAGATCCTAAAGAATCATTTAAAACGAGGACCTTCAAACAT
CAGAGAGTGGAAACTAAGTTGACCAGTGTACACCAGCTGAGATTGGACGTTGAGAACAAA
TGTAATATGAATATGAGGGAGATTCTGGCAAATCTCATTTTTATAGCCTGCATCGACTGC
GAGCGCTCCCTGATACAGCACTCAACAAAGCTTTATTTGTGTGACACTACTCGATTGACC
GAGGAGTTATTCTACGAAACCATTCTCTATGATTTCCAAAATCTCGGTTTAATTAAATTA
TCGAATCCGTTGCCCTTAGAGGAACTGTTGGTACTAGGACTCGGTTCGCACGAAGAGGAA
TGGGACAACGACTTAGGTGACATGACAGAAATGGCTGCACAGATGACAAAATTACTCATA
AGCAAAGGTCCCATGTTATATGAATATTTTTCGATGGAAATTAATAACAAAGGCGAGTTA
TTGTCTCTGCCTTTGCTATTAGACGGTCACACCCCCTTCATGGGAGCATTGCCAGTGTAC
TTAGTTAGACTAGTAACTGAAGTGAACTGGGAGTCGGAGAAGGAGTGTTTCGATACGTTC
AGTCGACAGACAGCTATATTTTATTCACAACCAAACAGAGATTCACCGGAAGACGTGTCT
GAGACCGAGTCCTGGAAACAGGAGCACATAATATTTCCAGCTATAAGAAGGAATTTCTTG
CCGCCTAGCAGTTTCGTCAGCAACGGATCTATACTACAAATAGCTAATTTATGCGACCTC
TATAAAGTGTTTGAGCGTTGTTAA
Protein sequence:
MCEPGIIRKLDEEVVNRIAAGEIVQRPANALKELIENSLDAHSNNIIITVKAGGLKYLQI
QDNGTGIRSDNLDIVCERFTTSKLKQYEDLQAISTYGFRGEALASISHIAHLTILTKTAN
EKCAYNEELFYETILYDFQNLGLIKLSNPLPLEELLVLGLGSHEEEWDNDLGDMTEMAAQ
MTKLLISKGPMLYEYFSMEINNKGELLSLPLLLDGHTPFMGALPVYLVRLVTEVNWESEK
ECFDTFSRQTAIFYSQPNRDSQEDVSETESWKQEHIIFPAIRRNFLPPSSFVSNGSILQI
ANLCDLYKARLPGATMVEEIIKKTTDGAKVYAKDLVRVDSDAQKIDKFFKVTTIDRSKEN
ETNETRNETTNQDSKERNEGTEAVEVIDNNEVIDETDDIINNSLVSEPNETKAKKYKTAI
SSNVTYIDPKESFKTRTFKHQRVETKLTSVHQLRLDVENKCNMNMREILANLIFIACIDC
ERSLIQHSTKLYLCDTTRLTEELFYETILYDFQNLGLIKLSNPLPLEELLVLGLGSHEEE
WDNDLGDMTEMAAQMTKLLISKGPMLYEYFSMEINNKGELLSLPLLLDGHTPFMGALPVY
LVRLVTEVNWESEKECFDTFSRQTAIFYSQPNRDSPEDVSETESWKQEHIIFPAIRRNFL
PPSSFVSNGSILQIANLCDLYKVFERC