| New model in OGS2.0 | DPOGS208891 |
|---|---|
| Genomic Position | scaffold53:- 183119-190891 |
| See gene structure | |
| CDS Length | 1320 |
| Paired RNAseq reads | 587 |
| Single RNAseq reads | 1860 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA002464 (6e-40) |
| Best Drosophila hit | pyrexia, isoform A (1e-08) |
| Best Human hit | NF-kappa-B inhibitor alpha (2e-18) |
| Best NR hit (blastp) | nuclear factor NF-kappa-B p110 subunit isoform 1 [Bombyx mori] (2e-77) |
| Best NR hit (blastx) | nuclear factor NF-kappa-B p110 subunit isoform 1 [Bombyx mori] (2e-66) |
| GeneOntology terms | GO:0051059 NF-kappaB binding GO:0043392 negative regulation of DNA binding GO:0042994 cytoplasmic sequestering of transcription factor GO:0005515 protein binding GO:0000060 protein import into nucleus, translocation GO:0045746 negative regulation of Notch signaling pathway GO:0045941 positive regulation of transcription GO:0010745 negative regulation of macrophage derived foam cell differentiation GO:0010875 positive regulation of cholesterol efflux GO:0008139 nuclear localization sequence binding GO:0031663 lipopolysaccharide-mediated signaling pathway GO:0032403 protein complex binding GO:0034142 toll-like receptor 4 signaling pathway GO:0042127 regulation of cell proliferation GO:0043330 response to exogenous dsRNA GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter GO:0032270 positive regulation of cellular protein metabolic process GO:0042345 regulation of NF-kappaB import into nucleus GO:0032496 response to lipopolysaccharide GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway GO:0010888 negative regulation of lipid storage GO:0042802 identical protein binding GO:0032495 response to muramyl dipeptide GO:0031625 ubiquitin protein ligase binding GO:0032088 negative regulation of NF-kappaB transcription factor activity GO:0005829 cytosol GO:0006916 anti-apoptosis GO:0045638 negative regulation of myeloid cell differentiation GO:0033256 I-kappaB/NF-kappaB complex GO:0044419 interspecies interaction between organisms GO:0006915 apoptosis GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway GO:0008134 transcription factor binding GO:0005737 cytoplasm GO:0005634 nucleus GO:0031072 heat shock protein binding GO:0007253 cytoplasmic sequestering of NF-kappaB |
| InterPro families | IPR020683 Ankyrin repeat-containing domain IPR011029 DEATH-like IPR002110 Ankyrin repeat |
| Orthology group | MCL23532 |
Nucleotide sequence:
ATGGTCGCCGATTCTGCAAAACGAAGCGAAAAGAACACAAAGTACAAGGAATCATTGAAG
TCGGAGGTAAAAGATGAACCGAAAAGCAATGTTATAAGAAAACCACCAAGTGAATACTCC
GCGCTCTATAAGGCGGAAGACGGAGTCGAAGTTCAGAAACTCATCAAGGAACTCTGTGAA
ATGATGAGAAACAAGGACGGTATCAAGAAGCAGGATGTGAGAAGCAAGTTGGACAGGCTC
TTGGAGATGAGACTGTCCAATGGTGACACTTTTCTCCACCTGACCCTGAGTAGTAATCAG
CCGAGCTTGGAATATATTGTGAAGTTGATTTATAACATGAAGATGACTAAGTTATTGAAC
TTGAAGAACAACCAAATGCAGACTGTACTGCATCTGGCTATTATCAATGATTCGCCGAAA
TTAGTCTCTTTCCTTATATCGAAAGGTTGTGATCCCATGGAGGAAGACAATGAAGGGAAT
AATGCACTGCATTATGCTGTCATATGTCAGACTTGCCTCGGACCGCTATTGGAATCCATC
AAGAGTAATAACATCAGTTACGATATAAACGCTTACAACAATGAGAAACAGACAGCTTTA
CATCTATCGTCGGTGTACGGTTGTCGTAAGAGCGCGACCTTGTTGTTGTCTGCTGGCGCG
AAATGGGACGCTCGCGATGGAGACGGCCGTACAGCCCTCCACCTCGCCGTACTCGACGAC
TGTTTACCAGTCGCAAATGAACTGCTAGAGAAGCCGGTGGATGTAGACGCCTTGGATGGA
AAAGGCTACACAGCGCTACAGATAGCCTGCGATAGTGTGATCAGAGAAAACACCTTAGAG
ATTGTGAAACTTTTACTAGACAAGAAGGCTGATCCCCTGAAACACGAAGAAAACAACCAT
TCCGCGTGGAGGCTGGCGCGAGATAAGCCACAACTAGCAAAACTTATGAGAAAATATATA
AGTTCAGAAAAAAATATAGAAATTGATATTAAATCTGAGCCGGAGGACGACGACGACTCG
GAAGAAAAGGATACAGAATCGGATCTTACAGCATTACCAATGTATATTGATCGGGTTGCA
GTCTTACTGGATAATAATGGAGGCTGGAAGGAATTAATGAGAAGGCTTGATAAGGATTCC
TATTACTCCTGGTATAAAGCCACTGACAGTCCCGCAAGAACACTCTTGAACCATCTTAAG
GGTTGGAATGAGGGTGTGTCTTCAAAGTCTTTGGCATTGTTGTTGGATGACATCGGACAA
CATGAAGCAGCAACTATTATTAAAGCCTGTATTGATGAACCAAATAAAAACCTTAAGTGA
Protein sequence:
MVADSAKRSEKNTKYKESLKSEVKDEPKSNVIRKPPSEYSALYKAEDGVEVQKLIKELCE
MMRNKDGIKKQDVRSKLDRLLEMRLSNGDTFLHLTLSSNQPSLEYIVKLIYNMKMTKLLN
LKNNQMQTVLHLAIINDSPKLVSFLISKGCDPMEEDNEGNNALHYAVICQTCLGPLLESI
KSNNISYDINAYNNEKQTALHLSSVYGCRKSATLLLSAGAKWDARDGDGRTALHLAVLDD
CLPVANELLEKPVDVDALDGKGYTALQIACDSVIRENTLEIVKLLLDKKADPLKHEENNH
SAWRLARDKPQLAKLMRKYISSEKNIEIDIKSEPEDDDDSEEKDTESDLTALPMYIDRVA
VLLDNNGGWKELMRRLDKDSYYSWYKATDSPARTLLNHLKGWNEGVSSKSLALLLDDIGQ
HEAATIIKACIDEPNKNLK