| New model in OGS2.0 | DPOGS200296 |
|---|---|
| Genomic Position | scaffold640:+ 151193-177237 |
| See gene structure | |
| CDS Length | 2952 |
| Paired RNAseq reads | 3548 |
| Single RNAseq reads | 8969 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA005570 (2e-123) |
| Best Drosophila hit | lethal (2) giant larvae, isoform A (0.0) |
| Best Human hit | lethal(2) giant larvae protein homolog 1 (0.0) |
| Best NR hit (blastp) | putative lethal (2) giant larvae [Heliconius melpomene] (0.0) |
| Best NR hit (blastx) | putative lethal (2) giant larvae [Heliconius melpomene] (0.0) |
| GeneOntology terms | GO:0005886 plasma membrane GO:0005578 proteinaceous extracellular matrix GO:0007391 dorsal closure GO:0005856 cytoskeleton GO:0005614 interstitial matrix GO:0042127 regulation of cell proliferation GO:0030154 cell differentiation GO:0030863 cortical cytoskeleton GO:0035072 ecdysone-mediated induction of salivary gland cell autophagic cell death GO:0035070 salivary gland histolysis GO:0016082 synaptic vesicle priming GO:0008021 synaptic vesicle GO:0007269 neurotransmitter secretion GO:0016336 establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016327 apicolateral plasma membrane GO:0016335 morphogenesis of larval imaginal disc epithelium GO:0005829 cytosol GO:0008283 cell proliferation GO:0016333 morphogenesis of follicular epithelium GO:0016334 establishment or maintenance of polarity of follicular epithelium GO:0045175 basal protein localization GO:0005938 cell cortex GO:0016332 establishment or maintenance of polarity of embryonic epithelium GO:0005737 cytoplasm GO:0007399 nervous system development GO:0045159 myosin II binding GO:0045184 establishment of protein localization GO:0017022 myosin binding GO:0007179 transforming growth factor beta receptor signaling pathway GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity GO:0005918 septate junction GO:0045196 establishment or maintenance of neuroblast polarity GO:0002009 morphogenesis of an epithelium GO:0007559 histolysis GO:0045200 establishment of neuroblast polarity GO:0019991 septate junction assembly GO:0008360 regulation of cell shape GO:0008105 asymmetric protein localization GO:0045167 asymmetric protein localization involved in cell fate determination GO:0008104 protein localization GO:0045746 negative regulation of Notch signaling pathway GO:0007423 sensory organ development GO:0045186 zonula adherens assembly GO:0005515 protein binding GO:0051726 regulation of cell cycle GO:0008285 negative regulation of cell proliferation GO:0001738 morphogenesis of a polarized epithelium GO:0016323 basolateral plasma membrane GO:0051668 localization within membrane GO:0007406 negative regulation of neuroblast proliferation GO:0016325 oocyte microtubule cytoskeleton organization GO:0007314 oocyte anterior/posterior axis specification GO:0030036 actin cytoskeleton organization GO:0055059 asymmetric neuroblast division |
| InterPro families | IPR019782 WD40 repeat 2 IPR019775 WD40 repeat, conserved site IPR000664 Lethal(2) giant larvae protein IPR011046 WD40 repeat-like-containing domain IPR015943 WD40/YVTN repeat-like-containing domain IPR013577 Lethal giant larvae homologue 2 IPR019781 WD40 repeat, subgroup IPR001680 WD40 repeat |
| Orthology group | MCL10984 |
Nucleotide sequence:
ATGGCCGGCAGAATGCTAAAGTTTATACGAGGGAAGGGCCAGCAGCCCTCTGCAGAGAGA
CAGAAACTGCAAAATGAACTATTCGCCTTCCGTAAGACAGTCCAACATGGCTTCCCTCAC
AGGGCGTCGGCGCTAGCCTGGGACCCGTTACTCCGCCTGGCAGCCCTCGGCACAGCGACG
GGAGCATTGAAAGTGTACGGAAGACCAGGCGTCGAGCTCTACGGACAGCACACCAATCCG
GAAGTTGTAGTCACCCAGATACATTTCATACCAGGAACAGGACGGCTCATATCACTCTGC
GATGATAACAGTCTCCATTTGTGGGAGATAAACGAGAAATCTCTAGTGGAACTCAAATCA
CATTCCTTCGAAGGAAAAAATAAGAAAATATCATCAATATGCGTCGAATCTTCTGGAAAC
AACCTCCTGCTTGGAACCGAGGGCGGAAATATATACTCCTTAGACTGCAACGCTTTCACA
ATACACGAAGACGTTATTTATCAGGACACTGTTATGCAAAACTGTCCAGAAGACTTCAAG
GTCAATCCAGGTGCAGTGGAATCTATATGCGAACACCCGAAGACACCAAGTCGATTACTA
ATAGGATACAACCGAGGGCTTGTGGTGTTATGGGACAGAGCGACCTCAGCGCCCTCACAC
ACCTTCGTCTCCAACCAACAGCTGGAGAGCTTGTGCTGGAACGATGAAGGAGAACACTTC
ACGTCGTCTCACAACGACGGTTCGTATGTGACGTGGGAGGTGGCGGGCGCCGCCAGTGAT
CGCCCGCTGAAGGAACCCGTGACTCCTTATGGACCTTACCCCTGTAAGGCCATCTCCAAA
ATACTGAATAGGACCAGCGTGGGAGGAGACGAGCTTATCATATTTGCAGGTGGTATGCCG
AGAGCTTCATATTCGGACAAGTACACAGTGACCGTCCAGCAAGGAGAAAAACACGTCGCT
TTCGACTTTACCAGCCGTGTGATAGACTTCTTTACAACAACTCCCGTGCCGCCCGACGGC
GTCCCTCTACAGGAGGAGCGCCCTACCATCCCCGCCGTCATACAAGGACAGGCAGTGAAC
CAAGTTGCCGCTACTCTGGTGGTGTTAGCTGAAGAGGAGCTGGTGGTGTTAGATCTGTGT
GATGAGAGATGGCGTCCGCTAAGACTGCCGTACCTGGTGTCGGTACACGCCTCCGCCATC
ACAACCGCTTACCTCGTCGACAACGTCGCCGACAATGTTTACGATAACATTGTGCAAGCG
GGTCAACAACAAACCGAAAACATTTACTCCGAGAGCCAGTGGCCTATCTCCGGAGGGATA
GTAGAAACGGCCGAACAGACAGACAAACAGATCCTGCTCACCGGCCACGAAGACGGCTCG
GTCCGCTTCTGGGACGTGACCGGCGTCGTCATGACGCCTCTATATAAATACACAACCGCC
CCACTCTTCAGCGGCGAAGAGATATGTGAAAATAACGACAGTCAAAACGACGAGGAAGAG
TGGCCGCCGTTCAGGAGAGTCGGCACATTTGACCCGTACAGTGACGACCCGCGACTGGCT
GTGAAAAGAGTCCTGCTCTGTCCGCTGTCTGGTATGCTAACTATCGGTGGCGCGGCTGGC
CACATTGTTATAGCGAGTCTGAAGTCCACACCAAGCACGGCGGAAGTAAAATCCGTATCC
GTGAACATCGTGTCTGACAGAGACGGCTTCGTATGGAAGGGTCACGATCAACTAAACCTC
CGTTCCGGACCGCTCACGTTCCCCGCCGGCTATCAAGCGAGCGCTGTGTGCCAGCTGTCC
CCGCCGGCCGCGGTGACAGCCCTGTCCGCGCAGTGGGAGTGGGGGGTGGTGGTGGCGGGC
ACGGCGCACGGCCTGGCACTCATCGACGCGCTCAAACCCGCGCCTCTCACACACAAGTGC
ACTCTCAACGCACACGGCCACTCCGGGGCGGGCGATACTCCTATTTCAAGAAGGAAATCA
TTCAAGAAATCACTCAGAGAATCCTTCCGAAGACTCAGGAAGGGGAGATCCCAGAGACGG
CAGACAACTACTTCAGCCAGTCCCACATCACCCACGCAGCCAGCTTCAAAAAAGATAACG
GAAAAGATAAATGAAGCGGACGCTGACGTCAAACCCATCGAAAGAGCCGTGGAAGCGAGG
TCCACTGACGACGCCTTCGGCACCATGGTGCGCTGTCTCTACTTCGCGAGGACCTTCCTT
GTCAGCACTCAGAACTCGACGCCCACATTATGGGCCGGCACTAACAATGGCACGGTTTAC
GCATTCACGATACACGTACCCAATACCAACAAGAGGAAAGAGGAACCCGTAACATGTCAA
CTAGCTAAGGAGATCCAGCTGAAGCATCGAGCCCCTGTGATAGGTATAACAGTGCTGGAC
GGAGCGTCCGTGCCGCTACCGGATCCTTTGGAGGTGGAGCGTGGCGTCGCACCTCTGCCG
GAGGCCGGGCCTCAGCGAGTCCTCATCACGTCGGAGGAGCAGTTCAAAGTGTTCACGCTG
CCGTCACTGAAGCCGCACAACAAATACAAGCTGACAGCACACGAGGGCGCCAGGGTGCGG
CGCACAGCGTTCGCGTGGTTCGAGTGCGGCGGAGGGTCGGAGCGGCACCGGGAGTGGTGT
CTGCTGTGTCTCACCAACCTGGGAGACTGTCTCGTGCTATCTCCTGACCTCAGGAGACAA
CTGAACGCGGCCGCCGTGCGCAAGGAAGACATTAATGGTATTTCCAGTCTGTGCTTCTCT
AAGCGAGGCGAGGCTCTCTACTTGCACTCCTCGTCCGAGTTGCAGAGGATAACGCTCTCC
GCGACTAAGGTGACCATAGCTCAATGCCACGTGTTGCTATCTCCATGGGCCGCCGCCCTC
CGCGGGCCGGCGGACGAGGCGCCGCTCACTAACGGCGAACACAAAGTGAGTTACTCATAT
AGCATACAATAA
Protein sequence:
MAGRMLKFIRGKGQQPSAERQKLQNELFAFRKTVQHGFPHRASALAWDPLLRLAALGTAT
GALKVYGRPGVELYGQHTNPEVVVTQIHFIPGTGRLISLCDDNSLHLWEINEKSLVELKS
HSFEGKNKKISSICVESSGNNLLLGTEGGNIYSLDCNAFTIHEDVIYQDTVMQNCPEDFK
VNPGAVESICEHPKTPSRLLIGYNRGLVVLWDRATSAPSHTFVSNQQLESLCWNDEGEHF
TSSHNDGSYVTWEVAGAASDRPLKEPVTPYGPYPCKAISKILNRTSVGGDELIIFAGGMP
RASYSDKYTVTVQQGEKHVAFDFTSRVIDFFTTTPVPPDGVPLQEERPTIPAVIQGQAVN
QVAATLVVLAEEELVVLDLCDERWRPLRLPYLVSVHASAITTAYLVDNVADNVYDNIVQA
GQQQTENIYSESQWPISGGIVETAEQTDKQILLTGHEDGSVRFWDVTGVVMTPLYKYTTA
PLFSGEEICENNDSQNDEEEWPPFRRVGTFDPYSDDPRLAVKRVLLCPLSGMLTIGGAAG
HIVIASLKSTPSTAEVKSVSVNIVSDRDGFVWKGHDQLNLRSGPLTFPAGYQASAVCQLS
PPAAVTALSAQWEWGVVVAGTAHGLALIDALKPAPLTHKCTLNAHGHSGAGDTPISRRKS
FKKSLRESFRRLRKGRSQRRQTTTSASPTSPTQPASKKITEKINEADADVKPIERAVEAR
STDDAFGTMVRCLYFARTFLVSTQNSTPTLWAGTNNGTVYAFTIHVPNTNKRKEEPVTCQ
LAKEIQLKHRAPVIGITVLDGASVPLPDPLEVERGVAPLPEAGPQRVLITSEEQFKVFTL
PSLKPHNKYKLTAHEGARVRRTAFAWFECGGGSERHREWCLLCLTNLGDCLVLSPDLRRQ
LNAAAVRKEDINGISSLCFSKRGEALYLHSSSELQRITLSATKVTIAQCHVLLSPWAAAL
RGPADEAPLTNGEHKVSYSYSIQ