| New model in OGS2.0 | DPOGS212475 |
|---|---|
| Genomic Position | scaffold2104:+ 6872-16503 |
| See gene structure | |
| CDS Length | 1362 |
| Paired RNAseq reads | 1905 |
| Single RNAseq reads | 4361 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA009650 (0.0) |
| Best Drosophila hit | smad on X (5e-128) |
| Best Human hit | mothers against decapentaplegic homolog 3 isoform 1 (2e-156) |
| Best NR hit (blastp) | GG17985 [Drosophila erecta] (0.0) |
| Best NR hit (blastx) | GG17985 [Drosophila erecta] (7e-180) |
| GeneOntology terms | GO:0000122 negative regulation of transcription from RNA polymerase II promoter GO:0001501 skeletal system development GO:0001657 ureteric bud development GO:0001666 response to hypoxia GO:0001701 in utero embryonic development GO:0001707 mesoderm formation GO:0001756 somitogenesis GO:0001836 release of cytochrome c from mitochondria GO:0001889 liver development GO:0001933 negative regulation of protein amino acid phosphorylation GO:0001947 heart looping GO:0002076 osteoblast development GO:0002520 immune system development GO:0003677 DNA binding GO:0003690 double-stranded DNA binding GO:0003700 sequence-specific DNA binding transcription factor activity GO:0003706 ligand-regulated transcription factor activity GO:0005160 transforming growth factor beta receptor binding GO:0005515 protein binding GO:0005518 collagen binding GO:0005622 intracellular GO:0005634 nucleus GO:0005637 nuclear inner membrane GO:0005654 nucleoplasm GO:0005667 transcription factor complex GO:0005737 cytoplasm GO:0005829 cytosol GO:0005886 plasma membrane GO:0006810 transport GO:0006917 induction of apoptosis GO:0006919 activation of caspase activity GO:0006955 immune response GO:0007050 cell cycle arrest GO:0007179 transforming growth factor beta receptor signaling pathway GO:0007183 SMAD protein complex assembly GO:0007369 gastrulation GO:0007492 endoderm development GO:0008013 beta-catenin binding GO:0008134 transcription factor binding GO:0008285 negative regulation of cell proliferation GO:0008633 activation of pro-apoptotic gene products GO:0008637 apoptotic mitochondrial changes GO:0009880 embryonic pattern specification GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter GO:0010694 positive regulation of alkaline phosphatase activity GO:0010718 positive regulation of epithelial to mesenchymal transition GO:0010843 promoter binding GO:0016202 regulation of striated muscle tissue development GO:0016563 transcription activator activity GO:0016566 specific transcriptional repressor activity GO:0017015 regulation of transforming growth factor beta receptor signaling pathway GO:0019049 evasion of host defenses by virus GO:0019901 protein kinase binding GO:0030308 negative regulation of cell growth GO:0030335 positive regulation of cell migration GO:0030501 positive regulation of bone mineralization GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030878 thyroid gland development GO:0031625 ubiquitin protein ligase binding GO:0032731 positive regulation of interleukin-1 beta production GO:0032909 regulation of transforming growth factor-beta2 production GO:0032916 positive regulation of transforming growth factor-beta3 production GO:0035413 positive regulation of catenin protein nuclear translocation GO:0042110 T cell activation GO:0042177 negative regulation of protein catabolic process GO:0042803 protein homodimerization activity GO:0042993 positive regulation of transcription factor import into nucleus GO:0043066 negative regulation of apoptosis GO:0043234 protein complex GO:0043235 receptor complex GO:0043565 sequence-specific DNA binding GO:0045216 cell-cell junction organization GO:0045668 negative regulation of osteoblast differentiation GO:0045893 positive regulation of transcription, DNA-dependent GO:0045930 negative regulation of mitotic cell cycle GO:0045941 positive regulation of transcription GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0046332 SMAD binding GO:0048340 paraxial mesoderm morphogenesis GO:0048589 developmental growth GO:0048617 embryonic foregut morphogenesis GO:0048701 embryonic cranial skeleton morphogenesis GO:0050678 regulation of epithelial cell proliferation GO:0050776 regulation of immune response GO:0050821 protein stabilization GO:0050927 positive regulation of positive chemotaxis GO:0051098 regulation of binding GO:0051496 positive regulation of stress fiber assembly GO:0051894 positive regulation of focal adhesion assembly GO:0060039 pericardium development GO:0060290 transdifferentiation GO:0070306 lens fiber cell differentiation GO:0070410 co-SMAD binding GO:0070412 R-SMAD binding GO:0090263 positive regulation of canonical Wnt receptor signaling pathway |
| InterPro families | IPR001132 SMAD domain, Dwarfin-type IPR003619 MAD homology 1, Dwarfin-type IPR013019 MAD homology, MH1 IPR017855 SMAD domain-like IPR013790 Dwarfin IPR008984 SMAD/FHA domain |
| Orthology group | MCL11214 |
Nucleotide sequence:
ATGTTTCCGCTAACTCCACCTGTTGTGAAGCGGCTGTTGGGGTGGAAGAAGGGCCCCGAG
GGTTCGACGGCTGAGGACAAATGGTCCGAAAAGGCCGTAAAAAGTTTAGTAAAAAAGTTA
AAGAAAAGCGGTGCGATTGAAGAATTAGAGAAGGCTCTGTCCAACCAAAATAGCCATACA
AAGTGTGTGACGATACCGAGGGTCAAACCGAATGATAATATAATAAATGGCCAGAACCGT
AAGGGATTGCCGCATGTGGTGTACTGTCGGTTGTGGCGTTGGCCGCAGCTTCAGAGCCAG
CATGAATTGAAGCCCGTGGATCACTGCGAGTACGCTTACCAGCTGAAGAAAGACGAAGTC
TGCATCAATCCATATCATTACAATAAAATTGATTCTCCAGCGTTACCCCCAATCTTGGTG
CCTCGTTGTCCCGAGGGGGAGATACGGGCCCCCCCGCCTTACGAATACCAGCATCACGAT
CACGACAGCGTGATGCAGAGCAGCGTGGGCGTGGTGGGCGTGGGTGTGGGCGCCGGCGTG
GGCGTGGGCGTCGGTGGTCACAGCGCTCTGTACCTGGAGGCGACTCTCGCTCAGCAGGTC
CCCGGGAACACCACCGTGCAGCTGAGTTCGTCGTCAGTGGAGACCCCTCCCCCCGGCTAC
ATGAGTGAGGACGGTGACCCCATGGACCACAACGACAATATGAATCTGACCCGGCTGACG
CCGTCCCCGTCCATGGCGACGGAGGCGGCCCCCGTGTTGTACCACGAGCCGGCCTTCTGG
TGCAGCATCAGCTACTACGAGCTGAACACTCGGGTGGGGGAGACCTTCCACGCCAGCCAG
CCCTCGATCACCGTGGACGGATTCACAGATCCCAGTAACAGTGAACGCTTCTGCCTCGGT
CTGCTCTCCAACGTGAATAGAAACGAAGTCGTCGAACAAACAAGGAGGCACATCGGGAAA
GGCGTCCGTCTGTATTATATCGGCGGCGAGGTTTTCGCTGAATGTCTCAGCGACTCGTCC
ATATTCGTACAGAGCCCGAACTGCAATCAGCGGTACGGCTGGCATCCGGCCACCGTCTGC
AAGATACCACCAGGCTGTAACCTGAAGATCTTCAACAACCAGGAGTTTGCTGCTCTCCTA
TCTCAGTCCGTGTCCCAGGGGTTCGAGGCTGTGTTCCAACTAACCAGGATGTGCACCATC
AGGATGAGCTTCGTCAAGGGATGGGGGGCGGAGTACCGTCGTCAAACGGTGACTTCAACT
CCGTGTTGGATCGAGCTGCATCTGAACGGTCCCCTTCAATGGCTGGACCGGGTCCTCACA
CAGATGGGGTCGCCGCCGCTGCCCTGCTCTTCTATGTCATAG
Protein sequence:
MFPLTPPVVKRLLGWKKGPEGSTAEDKWSEKAVKSLVKKLKKSGAIEELEKALSNQNSHT
KCVTIPRVKPNDNIINGQNRKGLPHVVYCRLWRWPQLQSQHELKPVDHCEYAYQLKKDEV
CINPYHYNKIDSPALPPILVPRCPEGEIRAPPPYEYQHHDHDSVMQSSVGVVGVGVGAGV
GVGVGGHSALYLEATLAQQVPGNTTVQLSSSSVETPPPGYMSEDGDPMDHNDNMNLTRLT
PSPSMATEAAPVLYHEPAFWCSISYYELNTRVGETFHASQPSITVDGFTDPSNSERFCLG
LLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYGWHPATVC
KIPPGCNLKIFNNQEFAALLSQSVSQGFEAVFQLTRMCTIRMSFVKGWGAEYRRQTVTST
PCWIELHLNGPLQWLDRVLTQMGSPPLPCSSMS