| New model in OGS2.0 | DPOGS207092 |
|---|---|
| Genomic Position | scaffold1:+ 2453265-2457924 |
| See gene structure | |
| CDS Length | 1791 |
| Paired RNAseq reads | 734 |
| Single RNAseq reads | 1669 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA014502 (0.0) |
| Best Drosophila hit | merlin (4e-137) |
| Best Human hit | merlin isoform 1 (2e-144) |
| Best NR hit (blastp) | PREDICTED: similar to ENSANGP00000016048 [Nasonia vitripennis] (0.0) |
| Best NR hit (blastx) | PREDICTED: similar to ENSANGP00000016048 [Nasonia vitripennis] (0.0) |
| GeneOntology terms | GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein GO:0043409 negative regulation of MAPKKK cascade GO:0019898 extrinsic to membrane GO:0008092 cytoskeletal protein binding GO:0007398 ectoderm development GO:0032154 cleavage furrow GO:0005912 adherens junction GO:0005886 plasma membrane GO:0008285 negative regulation of cell proliferation GO:0030027 lamellipodium GO:0030036 actin cytoskeleton organization GO:0030175 filopodium GO:0042475 odontogenesis of dentine-containing tooth GO:0048471 perinuclear region of cytoplasm GO:0005856 cytoskeleton GO:0014010 Schwann cell proliferation GO:0022408 negative regulation of cell-cell adhesion GO:0045216 cell-cell junction organization GO:0046426 negative regulation of JAK-STAT cascade GO:0070306 lens fiber cell differentiation GO:0001726 ruffle GO:0005730 nucleolus GO:0005634 nucleus GO:0005737 cytoplasm GO:0006469 negative regulation of protein kinase activity GO:0008156 negative regulation of DNA replication GO:0001707 mesoderm formation GO:0005769 early endosome GO:0035330 regulation of hippo signaling cascade GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein GO:0051496 positive regulation of stress fiber assembly |
| InterPro families | IPR019748 FERM central domain IPR008954 Moesin IPR019749 Band 4.1 domain IPR015788 Merlin IPR014352 FERM/acyl-CoA-binding protein, 3-helical bundle IPR011993 Pleckstrin homology-type IPR011259 Ezrin/radixin/moesin, C-terminal IPR018980 FERM, C-terminal PH-like domain IPR018979 FERM, N-terminal IPR000798 Ezrin/radixin/moesin family IPR019750 Band 4.1 family IPR019747 FERM conserved site IPR000299 FERM domain IPR011174 Ezrin/radixin/moesin |
| Orthology group | MCL12196 |
Nucleotide sequence:
ATGCCGCCTTTTAGAAGGAAGAAGGCTGCTAAGTCGTTCCCTGTTAAAGTTTGTACATTG
GATGCGGAATTAGAGTTTGACCTTGAGTGGAGAGCAACTGGCAGAGATTTATTTGATTTA
GTGTGCAGAACAATTGGCTTAAGAGAAACATGGTTCTTTGGGTTGCAATTTGAGGACACT
AAACATTTTATTAGTTGGCTGAAGTTAGATAAAAGAGTACAAGAACAATGCGTCTCACAA
ATGCCAGGGACACCATTTATGTTACTCTGCAAATTATATCCTGAAGATGTGGCCGAGGAG
CTGATCCAGGAAGTGACTCAACACCTCTTATTCCTACAGGTCAAGCAAGCCATACTGAAG
ATGGATATATACTGCCCACCTGAAGCCTCCGTTCTACTTGCAAGTTATGCTGTACAAGCT
AAGTATGGTGACTATGATGAAACAGCATCAAAACCAGGAATGTTAGCTAATGAGGATCTG
TTACCTCAAAGGGTCATCGATCAATACCAGATGACACCCGAAATGTGGGAGGAAAGGATC
AAGATATGGTATGCAGATCACAAAGGCATGTCAAGGGATGAAGCGGAAATGGAATATTTG
AAAATTGCTCAAGATCTGGACATGTATGGAGTTAACTATTTTGCTATTAATAATAAGAAG
GAAACCGATCTGTATCTGGGAGTCACAGCTTTAGGTCTGAATATATATGAGAAGGACAAT
AAGGTCACTCCCAAAACAACCTTCCCCTGGTCAGAGATTAAGCACATATCTTTTGATGAC
AAAAAGTTTGTTATAAAATTTGTGGACAAATCTGTGAATAATTTTATATTTTTCTCACCC
AAAGGGATGAATAAGCTGATCTTGGACCTTTGTATTGGCAACCATGACTTGTATATGCGG
CGACGGAAACCTGATACTATGGAGGTGCAGCAGATGAAGGCTCAGGCTAAGGAGGAGAAG
CAGCGTCGTCAGATAGAGCGTAACAAACTGTCCCGCGAGAAGCAGCTGCGTGAGGCGGCG
GAGCGGGAACGAGCTGCTATGGAGCAGCGTCTGTTACAGTACCAGGAGGAGATACGACTA
GCCAATGACGCTCTGCGTCGCTCAGAAGAAACAGCTGAGTTGTTGGCAGAGAAGGGTCGT
GTGGCTGAAGAAGAGGCTTCCTTGTTAGCACAGAAAGCGTCTGATGCGGAGAGGGAGAAC
GCTAGACTGAGACTCTCCGCGATACGCACTGAGGAGGAGAAGGTTCATCTAGAACGTAAG
ACGAGAGAAGCAGAGTTCCTAACGGCACGTCTCGTGGAAGAATCCGAGAAGAGAGCGGCG
GAGGCGGAAAGACTGAAGGCGGAGTTGGTAGCAGCTAGAGTAGCGGAGAAGCAAGCAAAA
GAGAAGCTGCTGAACTTCCTCAGTAGGACCTCAAATGGATCCCTGCCACCTCCGTCTGCG
AGCTCATCGCCGTTCCCGTCTTCATGTTCTCTACCAGCGGAACTGTCGGAGGCACCGTTG
GCTGACCCTGAGCTGACTGCGTACACCCTCGTCAGTGACGACGACCCTCACATACACAGG
CTCAGTGTTGAAATAGAAAAGGAACGTGTCGAATATCTGGCGAAGTCGAAGCACCTCCAA
CAACAGCTGGATGAGCTGCGCTGTGAGTTCTCAGTACTGAGGGTAGAGCAGGGCGGGTTG
GACCACCTCCATGATGTACAGGCTCGGGCCGGCGAGGACAAGTACAGTACACTGAGACGA
CTGAAGCAGGGCTCCACCAGGACGAGGGTCGCCTTCTATGAGGACCTGTAA
Protein sequence:
MPPFRRKKAAKSFPVKVCTLDAELEFDLEWRATGRDLFDLVCRTIGLRETWFFGLQFEDT
KHFISWLKLDKRVQEQCVSQMPGTPFMLLCKLYPEDVAEELIQEVTQHLLFLQVKQAILK
MDIYCPPEASVLLASYAVQAKYGDYDETASKPGMLANEDLLPQRVIDQYQMTPEMWEERI
KIWYADHKGMSRDEAEMEYLKIAQDLDMYGVNYFAINNKKETDLYLGVTALGLNIYEKDN
KVTPKTTFPWSEIKHISFDDKKFVIKFVDKSVNNFIFFSPKGMNKLILDLCIGNHDLYMR
RRKPDTMEVQQMKAQAKEEKQRRQIERNKLSREKQLREAAERERAAMEQRLLQYQEEIRL
ANDALRRSEETAELLAEKGRVAEEEASLLAQKASDAERENARLRLSAIRTEEEKVHLERK
TREAEFLTARLVEESEKRAAEAERLKAELVAARVAEKQAKEKLLNFLSRTSNGSLPPPSA
SSSPFPSSCSLPAELSEAPLADPELTAYTLVSDDDPHIHRLSVEIEKERVEYLAKSKHLQ
QQLDELRCEFSVLRVEQGGLDHLHDVQARAGEDKYSTLRRLKQGSTRTRVAFYEDL