| New model in OGS2.0 | DPOGS200403 |
|---|---|
| Genomic Position | scaffold1611:- 62126-74497 |
| See gene structure | |
| CDS Length | 1830 |
| Paired RNAseq reads | 731 |
| Single RNAseq reads | 1723 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA008980 (0.0) |
| Best Drosophila hit | TGF-beta activated kinase 1 (3e-89) |
| Best Human hit | mitogen-activated protein kinase kinase kinase 7 isoform A (3e-109) |
| Best NR hit (blastp) | PREDICTED: similar to Mitogen-activated protein kinase kinase kinase 7 (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) [Apis mellifera] (8e-128) |
| Best NR hit (blastx) | PREDICTED: similar to Mitogen-activated protein kinase kinase kinase 7 (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) [Apis mellifera] (2e-122) |
| GeneOntology terms | GO:0000165 MAPKKK cascade GO:0000166 nucleotide binding GO:0000186 activation of MAPKK activity GO:0000287 magnesium ion binding GO:0001525 angiogenesis GO:0001841 neural tube formation GO:0002726 positive regulation of T cell cytokine production GO:0004672 protein kinase activity GO:0004674 protein serine/threonine kinase activity GO:0004708 MAP kinase kinase activity GO:0004709 MAP kinase kinase kinase activity GO:0005515 protein binding GO:0005524 ATP binding GO:0005829 cytosol GO:0006468 protein amino acid phosphorylation GO:0007165 signal transduction GO:0007179 transforming growth factor beta receptor signaling pathway GO:0007250 activation of NF-kappaB-inducing kinase activity GO:0007252 I-kappaB phosphorylation GO:0008385 IkappaB kinase complex GO:0010008 endosome membrane GO:0016740 transferase activity GO:0032743 positive regulation of interleukin-2 production GO:0043066 negative regulation of apoptosis GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043507 positive regulation of JUN kinase activity GO:0046330 positive regulation of JNK cascade |
| InterPro families | IPR011009 Protein kinase-like domain IPR000719 Protein kinase, catalytic domain IPR001245 Serine-threonine/tyrosine-protein kinase IPR002290 Serine/threonine-protein kinase domain IPR020635 Tyrosine-protein kinase, catalytic domain IPR017441 Protein kinase, ATP binding site IPR008271 Serine/threonine-protein kinase, active site |
| Orthology group | MCL13350 |
Nucleotide sequence:
ATGGCTTCCAATGTGCAAGAGTCGCCTGTCGCTCAACAGACGTTTGTTGAAGAGATAGAT
TATAATGAAATTCAAGAATTACAGGTTGTAGGAAAGGGTGCATTTGGTGTAGTATGGAAG
GGACTGTGGCGAAATACTTTTGTGGCTGTGAAACATATCAATTCAGAATCTGAAAAGCGT
GAGTTTGCCATCGAAGTTCGTCAGTTGTCTCGTGTTTCGCACCCCAACATCGTGAGATTG
TACGGAGCATGCACGCAAGGCGCCCACGTCTGTCTTGTTATGGAGTACGCGGAAGGCGGC
TCATTGTACAACGTTCTCCACTGTCGACCAAAACCCAAATACTCCGCGGCCCATGCCATG
AGTTGGGCTCGACAGTGTGCCGAGGGTGTAGCTTATCTTCATGCAATGAAACCTAAACCA
CTAATACACAGGGATTTGAAACCACCAAATTTATTACTAGTTGCAGGAGGGCAGAAGCTT
AAAATATGTGATTTTGGAACTGCAGCTGATAAAGCTACATATATGACAAATAATAAAGGA
AGTGCGGCGTGGATGGCACCGGAGGTATTTGAAGGTTCTTCCTACACAGAGAAGTGTGAT
GTGTTTTCATGGGGTATAATATTATGGGAGGTGCTCTCTAGAAGGAAACCATTTGAAGAA
GGAGGTTCAGCATTCAGGATAATGTGGGCGGTGCACACAGGACAGAGACCAAATCTTATA
GAAGGTTGTCCGGAGCCTATAGAACAACTAATGACACAATGTTGGCATAAAATCCCCGCT
GAAAGACCCAGTATGGCCAAGGTAGTGGAAATAATGAAGGCGTTGTGCGATTTCTTTCCC
GGCGCTGATACACCGATAAACTTTGATGATCTTGAGGAGGAAGATGACAGTTTGGAAGAT
AAATATGTGATGTATGACACGCAGGACAGCTTCGACACAGACATGCAAAGCGACCAGAGC
AACCCCTTGCATTACACCGATGATGCAGCATCCAATCAGATATACAGGAACACTGGCCAA
TCATCACCGAGACCACGGAGCTTTGTGGAGACTCAAGTAAATAAGCTACAAAACCTAATG
GCCGCTGATGTTCAACCGAAGTCACCCAAAGAAGACGACTCCCACAGAGTTAGAATACCA
CAGCAGATCAAGAAATTGGATCAAAATGAGGCCGGCACCTCTATAACCATCAATAGGACG
TCCAGCTCTCCGATAAACTCTGATAGGAATGTGACAAGCGAGGGCAGCACGCCACAGGAC
ATATTACGAGTATACCGAAGCCCTAACATATTCAGTGAGAGTTCGTCGCCGCGAGGCATA
TCACCCATAGTTAACTACAACATCGGGAATATGAACCCTAGGCATATAGACATAGAGCAG
TATTGGAACAGAGAGAACGAGAAGCTATCACCATCAAGGACCCCATCGGCTTTAAGTAAC
ACCAATTCTATAAAGAAGGAAGATTATAATCAGAATTACTGTGACGGACTGAACGCAACC
AACAGTCCCATGAATCAGATCAGTGAATTCAACGGTAACTCCCCAAGGATGACCTTAGAT
CCCAGATATCAGACCCCGCTGCAAATTGAAGTTGATCCGAACGCGTGGGATCTGAAAGAT
TTCCGCGAACCGCTGGACTATGATGGTTACATTGAAGTGAGGAACAACGCTGGCTTAGAC
AAGTTTATAGCCGTCGGTATACCGGCGCAGAACGGGGTCGTCGAACTCTCGACTGCCCTG
CCAGCTCGAAGCAGAAAACCTCACGAAGGGCGGCTGTACACGGTGTCCGCATTTAGCTCC
GTCGGTTATGAGTCACAGTACCACGAATAG
Protein sequence:
MASNVQESPVAQQTFVEEIDYNEIQELQVVGKGAFGVVWKGLWRNTFVAVKHINSESEKR
EFAIEVRQLSRVSHPNIVRLYGACTQGAHVCLVMEYAEGGSLYNVLHCRPKPKYSAAHAM
SWARQCAEGVAYLHAMKPKPLIHRDLKPPNLLLVAGGQKLKICDFGTAADKATYMTNNKG
SAAWMAPEVFEGSSYTEKCDVFSWGIILWEVLSRRKPFEEGGSAFRIMWAVHTGQRPNLI
EGCPEPIEQLMTQCWHKIPAERPSMAKVVEIMKALCDFFPGADTPINFDDLEEEDDSLED
KYVMYDTQDSFDTDMQSDQSNPLHYTDDAASNQIYRNTGQSSPRPRSFVETQVNKLQNLM
AADVQPKSPKEDDSHRVRIPQQIKKLDQNEAGTSITINRTSSSPINSDRNVTSEGSTPQD
ILRVYRSPNIFSESSSPRGISPIVNYNIGNMNPRHIDIEQYWNRENEKLSPSRTPSALSN
TNSIKKEDYNQNYCDGLNATNSPMNQISEFNGNSPRMTLDPRYQTPLQIEVDPNAWDLKD
FREPLDYDGYIEVRNNAGLDKFIAVGIPAQNGVVELSTALPARSRKPHEGRLYTVSAFSS
VGYESQYHE