| New model in OGS2.0 | DPOGS211817 |
|---|---|
| Genomic Position | scaffold1181:- 54166-77423 |
| See gene structure | |
| CDS Length | 3672 |
| Paired RNAseq reads | 11474 |
| Single RNAseq reads | 26616 |
| Migratory profiles | Query via corresponding ESTs |
| Best Bmobyx hit | BGIBMGA008158 (5e-94) |
| Best Drosophila hit | RhoGEF2, isoform E (1e-34) |
| Best Human hit | rho guanine nucleotide exchange factor 11 isoform 1 (4e-40) |
| Best NR hit (blastp) | PREDICTED: similar to Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF) [Tribolium castaneum] (3e-62) |
| Best NR hit (blastx) | PREDICTED: similar to RhoGEF2 CG9635-PD, isoform D [Apis mellifera] (3e-53) |
| GeneOntology terms | GO:0005515 protein binding GO:0005622 intracellular GO:0007266 Rho protein signal transduction GO:0030010 establishment of cell polarity GO:0000910 cytokinesis GO:0045893 positive regulation of transcription, DNA-dependent GO:0007186 G-protein coupled receptor protein signaling pathway GO:0030036 actin cytoskeleton organization GO:0005085 guanyl-nucleotide exchange factor activity GO:0006915 apoptosis GO:0006928 cellular component movement GO:0006941 striated muscle contraction GO:0005737 cytoplasm GO:0005829 cytosol GO:0005089 Rho guanyl-nucleotide exchange factor activity GO:0005096 GTPase activator activity GO:0008624 induction of apoptosis by extracellular signals GO:0001558 regulation of cell growth GO:0001664 G-protein-coupled receptor binding GO:0005886 plasma membrane GO:0035023 regulation of Rho protein signal transduction GO:0004871 signal transducer activity |
| InterPro families | IPR000219 Dbl homology (DH) domain IPR011993 Pleckstrin homology-type |
| Orthology group | MCL10325 |
Nucleotide sequence:
ATGATGTGGTTCAAGAGGGACTCTAAAGTCCCCGAGAAGGACAACGTAGTTAATAAACTG
AAGAAGAAGAAACCGGTTCTACTGAAACCGACCCGCGAGTCCAGTGAGAGGGAAACCTCG
GCCGATAGTGACAAGGAGAAGAGACGGTACTCTGATATACTGGACATGAGAGTGTCGCTC
GAGCGGAGAGACGAGAGCGACGAGTCACTGTACGAGTCGGCCGACTGCCACAGTGACGCC
ATATCGGCCAGCGATGACGCTCTGCCCGCCCTGGGAAAGACGCCCACCATCAGCAAGGAG
TCGCTGAAACTGGCGGTCACCGACGAAGAGGGGGACCTGTCCAGGAACAGGAGGGGGCAC
AGGAAGACGATGTCACTGTCGAACCCCCTGGAGATAGTGAAGACGTGGGGAGACGAGTGG
TTCGACCACAAGCAGACGAGACAAGAAATCGACAAGAATTGTGACAAGAAGAAGTCTAGG
GAGAGTCTGTGGAGTGAAGAGGACAGAGAATCGATCTACGGCTCCACCGCTAAGTTGGAT
CAGATCAGAAAGAATAGCAAGAAGGAAGACAAGCAAAGTGACAGCAGCAGAAAGAGCAGC
ACCACCGAGCCTCCCAAACGGAAGACTAGCAAGGTGTCCTCGGTAGGCGCTCTTAACTTC
TTACGACGAAAGAAAACACCGACCTCGATGAAAGCCGTCGAGGCCGTCGTCGAAGTAGTC
GATGGAATAGTTAACACTGATGAGATTCTGAACAGAACTAAGTTCTTCTTGGAGGAAGAA
AAGAGATTCTGTTCAGTGAGTCAGGGGAAACCTCCAGTGGAGACCGACTCCGAGGAAGAG
ATGCCGCCTCCCAAGGTCATAGGAGAGCACAGGAGACGGTTGAGTAGACAGACGTCGAGG
AGTAAGAGCAAGGTTAGGGGGAAGAGTCAGAGCGTTAAAGTGAATACGTTGAGGAAGACG
CACAGTGCGACCTTGAAGAAGGCGAAGAAGAAGAATGGAAAGATTCCTCTCGCGAGTAGA
AGCAGACAAGCGAGCATCGTAGACCAGAGTCTGGTCGTCAAGAAATGTCCGGAGACCGCG
AAGCAGAACTCATGGCTGTTCAGCGGAAAAGGTGATTCCCGGAGAGAGGGCTCCACTGAC
GAGCCGGCCACCGGAGATGTAGACGGAGACGCCAACGACACGCCGCGGGAGATAGAGAAA
GAGAACAATCTGAAGAGCAGTTCCCGCGGAGTGAACCGCGCGGAGAGTTGCCGCGAGAGA
GACGCGCCGCGGAGAGGGAAACACAGGAACGCCTCCGACCCCAACAGGCTGACGGCGCAT
CATCACCATGACCTGGAACCAGGTGCGGCGACAGCTCCCTCAGGCAGCTCCAGCAGTTCG
AGTCTGTCCTCCAGGAGTAATGAGAGTAACACCGTGGCGGCTGAACAACAAGCTTCGCAG
TCGGACTGGTCGGAGGAGGAAGATCCTCTGGCCGCCCAGTGGTCGGACAGCTTGCCGCCC
GCCATCAGGGACTCGCTGGTACTCTCCGCCAGGATAAGGAAGAGACAGGAGGTTATACAC
GAACTGATAGTATCAGAAGGGTCTCACGTGCGGTGGTTGAAGGTTCTGGGGGTGGACTTC
CTCAAGCCGCTAGAGCGTCAACCGTCCCTCCTGCCTGCGGAGGAGCTGCGGGCTCTGTTC
CCTAACCTGCCCGGGGTCAGAGAGAGACATACCAAGTTGTACGCGGACCTCAGGGCCGTC
AGGAATGAAGCTCCTAATCACGTAGTACAAATAGGACCCGTCGCAGACGCCATGCTGAAT
ACTCTGGGCGAGGCGGGGTATGCTCCGTGTTTGTCCAAGTTCTGTCGAGGTCAACGAATG
GCTCTCGACTCCTTGCGGGAGAGGAGGAGGAAGAACAAGGAGCTGCAAGCGTTCCTCGCG
GGGAGGGAGCAGTTGCCGAGGTGCGGCCGCCTGCAGCTCCGGGACCTGTTGGCCTGTGTG
TGGCAGAGATTGACGAAATACCAACTGTTGCTGGAGAGCATTCTCAGAACGGCCGTGGAG
TGTGACGATGAAGACGGAGACAGTCCGGAAGAAGTGGCGAGACTTAGGAAGGCGCTCACC
GTGGCCAAGGACGTGCTGCAGAGTGTCGATACCGCCATACGGACCGCAGAGAACGAGCAC
AGACTGAGGGTGATCCAGTCCAAGCTGGAGGTGCGCGCGGGGGTGGGCGGCGCGGAGTGC
GAGGAGCTGCGGCGCCTGGAGCTGCCCCAGCACCGGCTGCTCCACGAAGGCGAGCTGTAT
CTGAGGACGGACTCCAAGCGCTCGGCCGTGCTGGCGCTGCTGCTGGCCGACTGCCTGGTG
CTGCTGCAACGGGAGGGGGAGCGGTTCCTACTGAAGCCCGTGGCCCAGCCCAGCCACGCT
GCTATGCTGTCGCCGCTCATCAAGTGGGAGAGAGTCCTGTTTCGTCCGAACGCCGCCGTT
AAGAACACGTTCTTCCTCATGAACATCAACGGTATTCAGATGCACGAGCTGTCCGCCAAC
ACGGCCGCCGAGTACGCCACCTGGGTGAAGTTGATCCAGGAAGCTCCCCTCGCCCGCCTG
GCGGAGTCCAAGCCGATCGCCTCTCACGGACACTCGCGCTCCACGGACGACTCCGGTATA
AATGTATCCCGGAACCCCTCGGACGCCTCGGAGAAGTCGACGTCCAGCGCCCCGCCCATG
TGTGAGAGCGAGAGGGATGTATCGCTAGAGCGAGACGACAAGCATGAGGAGAAGACCATG
GAGACAGAAGACGGAAGCGAGAAGAGAATGGAGAGGGGAGATAGAGACGAGAGAGACGTG
GAGAGACCCGCCGACCAAGAGGACAGGAACAGCGTGCCGGTGGTGGGCAGTAACTCTATC
CACCTGTTCTCGCCATCCGCGCTGGAGTCGTCCGCCGCCCTGGTAGTGACGCCGCCCGCA
CACGCACACCACGCCACCAGGGTCTACTCGCACCACGAGAGACTCCGTCGCCTGGACGAG
GTCATCAGTCGCACGTTGAAGGCGAAGAGTGCCGTGGTGGCCGAGGTGCTCGGGATCCCG
GCACAGAACTACAGGCACCTGGCCGAGCTGGCCGTGGCCGAGACCCTGGGACAAGTCGAC
ATCTGCGGGGAGCTGCCGGCGCCCAGAGACGCCGAGCCCGGCGCCGACCTTCACACGCTG
CTACTGGCCGCCCAGACACAAGCTAACCAGCTGTCGGAGTCTCTGAGCGCCGCCCTGTCT
TCGTCCGAGACGGGGCTGGTGTTGGCTCGCTCCGGGCGGTGTGACTCGTGCGTCAGACAT
ACCAGAGAAGTGTCCCCGGAGCCGGATCGTGAGGGTCGTGCGTCGTGTCGTGTGTCGTGT
CGTGACGACCGTGACTCGCTCGACGACTCCACCGACCACCGCCTGGAACATCTCATGGAT
GGTTCGATGTCGGCGGCGGCGCTGGCGACCCGGCTGGTGGGCGGTGTGTGCGGCCTTCAG
AGCACCCTGGCTGCTCTGTTGGCTGCTCTGCCGGCCGTCGAGAGGGATCGCGACCAGCTG
CGGGCCGAGCTGGCCGTGCTGCGGGAGAGGAGCGACCGGGAGCGGAGAGATTACCACCAC
CCGGCGGAAGACATATTCAGCAAGGGCTCCCTGGAGCAGTCCTTCCAGGAGCACCCCAGT
AACGGCGGTTGA
Protein sequence:
MMWFKRDSKVPEKDNVVNKLKKKKPVLLKPTRESSERETSADSDKEKRRYSDILDMRVSL
ERRDESDESLYESADCHSDAISASDDALPALGKTPTISKESLKLAVTDEEGDLSRNRRGH
RKTMSLSNPLEIVKTWGDEWFDHKQTRQEIDKNCDKKKSRESLWSEEDRESIYGSTAKLD
QIRKNSKKEDKQSDSSRKSSTTEPPKRKTSKVSSVGALNFLRRKKTPTSMKAVEAVVEVV
DGIVNTDEILNRTKFFLEEEKRFCSVSQGKPPVETDSEEEMPPPKVIGEHRRRLSRQTSR
SKSKVRGKSQSVKVNTLRKTHSATLKKAKKKNGKIPLASRSRQASIVDQSLVVKKCPETA
KQNSWLFSGKGDSRREGSTDEPATGDVDGDANDTPREIEKENNLKSSSRGVNRAESCRER
DAPRRGKHRNASDPNRLTAHHHHDLEPGAATAPSGSSSSSSLSSRSNESNTVAAEQQASQ
SDWSEEEDPLAAQWSDSLPPAIRDSLVLSARIRKRQEVIHELIVSEGSHVRWLKVLGVDF
LKPLERQPSLLPAEELRALFPNLPGVRERHTKLYADLRAVRNEAPNHVVQIGPVADAMLN
TLGEAGYAPCLSKFCRGQRMALDSLRERRRKNKELQAFLAGREQLPRCGRLQLRDLLACV
WQRLTKYQLLLESILRTAVECDDEDGDSPEEVARLRKALTVAKDVLQSVDTAIRTAENEH
RLRVIQSKLEVRAGVGGAECEELRRLELPQHRLLHEGELYLRTDSKRSAVLALLLADCLV
LLQREGERFLLKPVAQPSHAAMLSPLIKWERVLFRPNAAVKNTFFLMNINGIQMHELSAN
TAAEYATWVKLIQEAPLARLAESKPIASHGHSRSTDDSGINVSRNPSDASEKSTSSAPPM
CESERDVSLERDDKHEEKTMETEDGSEKRMERGDRDERDVERPADQEDRNSVPVVGSNSI
HLFSPSALESSAALVVTPPAHAHHATRVYSHHERLRRLDEVISRTLKAKSAVVAEVLGIP
AQNYRHLAELAVAETLGQVDICGELPAPRDAEPGADLHTLLLAAQTQANQLSESLSAALS
SSETGLVLARSGRCDSCVRHTREVSPEPDREGRASCRVSCRDDRDSLDDSTDHRLEHLMD
GSMSAAALATRLVGGVCGLQSTLAALLAALPAVERDRDQLRAELAVLRERSDRERRDYHH
PAEDIFSKGSLEQSFQEHPSNGG