| id | GO:0008534 Detailed information
|
|---|
| name | oxidized purine base lesion DNA N-glycosylase activity
|
|---|
| namespace | molecular_function
|
|---|
| alt_id | GO:0003907
|
|---|
| def | "Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296]
|
|---|
| comment | Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'.
|
|---|
| subset | gosubset_prok
|
|---|
| is_a | GO:0000702 ! oxidized base lesion DNA N-glycosylase activity
|
|---|
| is_a | GO:0003906 ! DNA-(apurinic or apyrimidinic site) lyase activity
|
|---|