id | GO:0038023   Detailed information
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  name | signaling receptor activity
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  namespace | molecular_function
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  def | "Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response." [GOC:bf, GOC:signaling]
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  comment | Note that this term and its child terms are intended for receptors that are directly coupled to a signal transduction pathway. This term should therefore not be used to annotate decoy receptors and other proteins that bind a signal but do not pass the signal on. This term can be used to annotate dependence receptors that transduce a signal when a ligand is withdrawn (in this case, signal withdrawal is considered to be the initiating signal), or receptors that signal at a basal level in the absence of a bound agonist. For receptors that mediate transport of a substance into the cell by receptor-mediated endocytosis, consider instead the term 'cargo receptor activity ; GO:0038024' and its children.
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  is_a | GO:0004871 ! signal transducer activity
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  is_a | GO:0004872 ! receptor activity
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  intersection_of | GO:0004872 ! receptor activity
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  intersection_of | part_of GO:0007165 ! signal transduction
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  created_by | rfoulger
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  creation_date | 2011-08-01T02:45:27Z
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