MonarchBase - Protein-coding gene

DPOGS200982
Transcript	DPOGS200982-TA	5553 bp
Protein	DPOGS200982-PA	1850 aa
Genomic position	DPSCF300147 - 431726-467108
RNAseq coverage	2154x (Rank: top 6%)

Annotation
*Heliconius*	HMEL011825	68.39%
*Bombyx*	BGIBMGA009049-TA	65.10%
*Drosophila*	Npc1a-PC	53.83%
EBI UniRef50	UniRef50_E2AJ59	56.09%	Niemann-Pick C1 protein n=2 Tax=Endopterygota RepID=E2AJ59_CAMFO
NCBI RefSeq	XP_624752.2	55.63%	PREDICTED: similar to Niemann-Pick Type C-1 CG5722-PA isoform 2 [Apis mellifera]
NCBI nr blastp	gi\|383847243	55.25%	PREDICTED: niemann-Pick C1 protein-like [Megachile rotundata]
NCBI nr blastx	gi\|307194536	56.73%	Niemann-Pick C1 protein [Harpegnathos saltator]

Group
Gene Ontology	GO:0016021	0	integral to membrane
	GO:0030301	0	cholesterol transport
	GO:0016020	3.2e-23	membrane
	GO:0008158	3.2e-23	hedgehog receptor activity
KEGG pathway	ame:552375	0.0
	K12385 (NPC1)	maps->	Lysosome
InterPro domain	[700-1819] IPR004765	0	Niemann-Pick C type protein
	[504-671] IPR003392	3.2e-23	Patched
Orthology group	MCL10165		Multiple-copy universal gene

Nucleotide sequence:

>DPOGS200982-TA
ATGGCTGAAATGGGAGGATTGTTTTCGCGAAGATTTCTACCAACCATCTTTGGCTGTCTGTTTCTATTATACGTAGCGGAATACATTCCGAGCGCGTCCGCTGAGGGCCACTGCATCTGGTACGGAGTGTGCTCTCAGCCAACCGATATAAAGAAATTGAATTGTTTGTACAATGGTACCGCCAAGCCTATTGAAGACGGAACAGCGAGGCAAACCCTTGAGAAATTCTGTCCGGATATAGCGGCCGGTGACGTCAGCTGTTGTGATGCCGACCAGCTCAAGAACTTCAACGCCAACATCGGCATAGCCTTGAACCTGTTGAACAGGTGTCCGACTTGCGTTAACAACTTCCTCAAACACATCTGCGCCCTCACCTGTTCACCAAAACAGAGCGAATTTTTAAATCCCGTCAAGATCGAGCCTTATAATGCCACTCATCAGCGTATAACAGAAGTTGACTATTACCTCGGTGCTACCTATATGAATGTGACGTTTGAGTCATGTGCAAGTGTCCAGATGCCGTCATCCAACCAGCTGGCTTTGGATCTGATGTGCGGTGACTATGGCGCAGAGTTCTGCACACCTCAGAGACTGTTCGACTTTATGGGTGATGCGGCCGACAGTCTGTACGTGCCCTTCCAGATAAACTACATCAGTGGGGACGAGCCTAAGGACGGGTTCACACCGCAGAACCCCTCCGTCCTGCCGTGCAGTGTTGGACTACCGGGTCAACCAGGGTGTTCGTGTTTGGACTGTCTAGCGTCCTGCCCCGCGCCCCCTCCAGCCCCGCCTGCGCCGGTTCCCTTCACGATAGCCGGGGCCGACGGGTACGCAGTCGTCATGGCCATCGTCTTCCTCATATTCTCCACGCTGTTCCTCAGCGGAGTGTATTGCTGTAACCAGCAGGAAAACTCAGTCGGCGTGGGTTCAGAGAACAATCAAGAGATGACCACCAATCCCACGGCCGTCGGTTGGTCTATCGAGCAGGCGGACGGAGGCGAGGCGAGTTTCTTTGAGAAGCTAGGGGCTGATACCGAGACCAAACTCGAAGACTTCTTCCAATGGTGGGGCTGCATCATGGCGTCCAGCCCATGGATCGTGCTATTCTTCGGCCTGTGTTTCGTGGTGGCTTTAGGTCACGGCATCAAATACATGATAGTCACGACGAACCCGGTGGAACTGTGGGCGTCTCCTAATTCGAGATCCCGTTTGGAGAGGGAGTACTTCGATTACCACTTCCGGCCGTTCTACAGGTCAGAGATGCTCATCATCAGCTCCAAGGGTCTGCCGGATGTGGAATACAAGGCGCCGGATGGGACCGTCATGCAGTTCGGACCGGTTTTCAATTCACAGTTCCTGTTTGACGTCCTCGACCTCCAGAATAGGATCATGGGTGAGTTCCAGACGCGTGTTGTGAGGATCAACCCGTTCTCGTGCCTGTCCGTGTGGGGCGGACCGGTGTCCCCGGGCGTAGTGCTGGGCGGCTTCCTGTCCCCGGGCGAGCCCCTTACTAAGTCGTCCAAGTTCCACCGCGCCAACGCTCTCATCCTGACCTTCCTAGTGGATAATCATCACGACAAAGAAAAGCTGAAGCCGGCGTTGGAGTGGGAGAAGGAGTTCATAAAGTTCATGAAGAACTACACGGAGAACGAGATGCCTTCATACATGGACATCGCGTACACGTCCGAGAGGTCCATCGAGGACGAGCTGGACCGCGAGTCGCAGTCCGACGTGTCCACCATCCTCGTGTCTTACTTCATCATGTTCGCATACATCGCCATATCCTTGGGACGGTTCACCACCTGCTCTAGGCTCCTCATCGATAGCAAGGTCACCCTCGGTCTCGGAGGTGTGTTGATCGTGCTGGCGTCCGTGGTGTGTTCTGTGGGCCTGTTCGGTTTCTTCGGAGTGGCCGCGACGCTGATCATCATGGAGGTGATCCCGTTCCTGGTGCTGGCGGTGGGTGTGGACAACATCTTCATCCTGGTCCAGACCAGCCAGAGAGAGCCGAGGAGGCCGGATGAGACCATCGCACAGCACATCGGAAGAACTTGTATATTGCAGCAAACCCTTGAGAAATTCTGTCCGGATATAGCGGCTGGTGACGTCAGCTGTTGTGATGCCGACCAGCTCAAGAACTTCAACGCCAACATCGGCATAGCCTTGAACCTGTTGAACAGGTGTCCGACTTGCGTTAACAACTTCCTCAAACACATCTGCGCCCTCACCTGTTCACCAAAACAGAGCGAATTTTTAAATCCCGTCAAGATCGAGCCTTATAATGCCACCCATCAGCGTATAACAGAAGTTGACTATTACCTCGGTGCTACCTATATGAATGTGACATTTGAGTCATGTGCAAGTGTCCAGATGCCGTCATCCAACCAGCTGGCTTTGGATCTGATGTGCGGTGACTATGGCGCAGAGTTCTGCACACCTCAGAGACTGTTCGACTTTATGGGTGATGCGGCCGACAGTCTGTACGTGCCCTTCCAGATAAACTACATCAGTGGGGACGAGCCTAAGGACGGGTTCACACCGCAGAACCCCTCCGTCCTGCCGTGCAGTGTTGGACTACCGGGTCAACCAGGGTGTTCGTGTTTGGACTGTCTAGCGTCCTGCCCCGCGCCCCCTCCAGCCCCGCCTGCGCCGGTTCCCTTCACGATAGCCGGGGCCGACGGGTACGCAGTCGTCATGGCCATCGTCTTCCTCATATTCTCCACGCTGTTCCTCAGCGGAGTGTATTGCTGTAACCAGCAGGAAAACTCAGTCGGCGTGGGTTCAGAGAACAATCAAGAGATGACCACCAATCCTACGGCCGTCGGTTGGTCTATCGAGCAGGCGGACGGAGGCGAGGCGAGTTTCTTTGAGAAGCTAGGGGCTGATACCGAGACCAAACTCGAAGACTTCTTCCAATGGTGGGGCTGCATCATGGCGTCCAGCCCATGGATCGTGCTATTCTTCGGCCTGTGTTTCGTGGTGGCTTTAGGTCACGGCATCAAGTACATGATAGTCACGACGAACCCGGTGGAACTGTGGGCGTCTCCTAATTCGAGATCCCGTATGGAGAGGGAGTACTTCGATTACCACTTCCGGCCGTTCTACAGGTCAGAGATGCTCATCATCAGCTCCAAGGGTCTGCCGGATGTGGAATACAAGGCGCCGGATGGGACCGTCATGCAGTTCGGACCGGTTTTCAATTCACAGTTCCTGTTTGACGTCCTCGACCTCCAGAATAGGATCATGGGTCTAGGTAACGAGACTCGTATACAGGACGTGTGTTACGCCCCGATGTCGTCTCCGTTCGAGGGGCCGGTGACCCCTGAGCAGTGCGGGGTCATGTCAGTGTGGGGCTGGTGGGAGAACAACCCCGACAACGTCAGGGACGATCTGGAGAACAATGAGTACCTGTCCAAGATCCTCTCGTGTGCACAACAAGTCAATCTGTATTTCTGCGATCAGATTTTTTTTTCAATATATATATATATATATATAGTGTGGGGCGGACCGGTGTCCCCGGGCGTAGTGCTGGGCGGCTTCCTGTCCCCGGGCGAGCCCCTTACTAAGTCGTCCAAGTTCCACCGCGCCAACGCTCTCATCCTGACCTTCCTAGTGGATAATCATCACGACAAAGAAAAGCTGAAGCCGGCGTTGGAGTGGGAGAAGGAGTTCATAAAGTTCATGAAGAACTACACGGAGAACGAGATGCCTTCATACATGGACATCGCGTACACGTCCGAGAGGTCCATCGAGGACGAGCTGGACCGCGAGTCGCAGTCCGACGTGTCCACCATCCTCGTGTCTTACTTCATCATGTTCGCATACATCGCCATATCCTTGGGACGGTTCACCACCTGCTCTAGGCTCCTCATCGATAGCAAGGTCACCCTCGGTCTCGGAGGTGTGTTGATCGTGCTGGCGTCCGTGGTGTGTTCTGTGGGCCTGTTCGGTTTCTTCGGAGTGGCCGCGACGCTGATCATCATGGAGGTGATCCCGTTCCTGGTGCTGGCGGTGGGTGTGGACAACATCTTCATCCTGGTCCAGACCAGCCAGAGAGAGCCGAGGAGGCCGGATGAGACCATCGCACAGCACATCGGAAGAACCCTGGGTCAGGTGGGTCCATCGATGTTCCTGACCTCGGTGTCGGAGTCCGTGTGTTTCTTCCTGGGCGCCCTGAGCGACATGCCGGCGGTGCGAGCCTTCGCCCTGTACGCGGGCGCCGCCCTCTTGGTCGACTTCCTGCTACAGATCACATGCTTCGTGGCGCTCCTGGCTCTGGATACGAGAAGACAGAACGACAACAGGTTCGACGTGTTCTGTTGTTTGTCTGGCGCCAAGTCCGAGGCGGCGGAGGTGGCGGGCGAGGGCGGGCTGTACAACCTGTTCCGCTACGTGTACGTCCCCTTCCTCATGAAGAGGGAGGTGCGCGCGTCCGTTATGATCATATTCTTCGCATGGCTCTGCTCCTCTGTAGCTGTGGCGCCTCACATAGACATCGGTCTAGACCAAGAGCTGTCGATGCCTCAGGACAGCTTCCAGACGAAATACTTCCAGCATCTCAACAAGTTCCTCAACATGGGTCTGCCTGTGTTCTTCGTCGTCACGGAGGGATTGAATTACTCGGATCAGAACACTCAGAATATGATATGCGGAACAAGATACTGCAACGACGACAGTCTGTCCATGCAGCTATATGCTGCCTCCCGCATATCGAACGTGTCGTACATCGCCCAGCCTCCGAACTCTTGGTTGGACGACTTCTTCGAGTGGTCGTCGCTGCCTTCCTGCTGCAAACGGTTCCCAGGAAACGATAGCTTCTGTCCAAACAATTACGGACCTGATAAATGCCAGCAGTGTAATATACCGCTGGTGGGTCCAGAGCAGCGACCAGCTCTGGCCGACTTCAACCACTACCTGCCGTTCTTCCTCCAAGACAACCCCACCCCTCAATGTCCAAAAGGCGGGCACGCGGCCTACGGTCGTTCAGTCAATTACATCGCCAACAACAAGGGCATCAGTCGCGTCGGCGCTACTTATTACCAAGCGTACCACACAGTCCTTAAGACGAGCAGTGACTACTACTCGGCGATGCGAGCCGCTCGTTCCATCGCCGCCAACCTAACGGCGACCCTGAACCGTAACGCCAACACGACCGTGAACGTTTTCCCCTACTCCGTGTTCTACGTGTTCTACGAACAGTACCTCACCATGTGGCCGGACACGCTCAAGTCGATGGGCATATCTGTGCTATCCATTTTCCTTGTCACCTTCGTCTTGATGGGCTTCGACTTATTCTCGGCCTTGGTTGTTGTTATAACCATCACCATGATAGTGGTGAACCTCGGCGGCCTCATGTACTGGTGGAACATCAGTCTCAACGCTGTCTCACTCGTTAACTTGGTGATGGCGGTGGGTATAGCGGTGGAGTTCTGCTCGCACTTGGTGCACTCGTTCAGTGTGTTCTACTTCCGTATGTACCTGGGAATTGTGTTGTTCGGAGCCGCCCATGGCCTGATCTTCCTTCCCGTCATGCTCAGCTACATTGGTAAGTGA

Protein sequence:

>DPOGS200982-PA
MAEMGGLFSRRFLPTIFGCLFLLYVAEYIPSASAEGHCIWYGVCSQPTDIKKLNCLYNGTAKPIEDGTARQTLEKFCPDIAAGDVSCCDADQLKNFNANIGIALNLLNRCPTCVNNFLKHICALTCSPKQSEFLNPVKIEPYNATHQRITEVDYYLGATYMNVTFESCASVQMPSSNQLALDLMCGDYGAEFCTPQRLFDFMGDAADSLYVPFQINYISGDEPKDGFTPQNPSVLPCSVGLPGQPGCSCLDCLASCPAPPPAPPAPVPFTIAGADGYAVVMAIVFLIFSTLFLSGVYCCNQQENSVGVGSENNQEMTTNPTAVGWSIEQADGGEASFFEKLGADTETKLEDFFQWWGCIMASSPWIVLFFGLCFVVALGHGIKYMIVTTNPVELWASPNSRSRLEREYFDYHFRPFYRSEMLIISSKGLPDVEYKAPDGTVMQFGPVFNSQFLFDVLDLQNRIMGEFQTRVVRINPFSCLSVWGGPVSPGVVLGGFLSPGEPLTKSSKFHRANALILTFLVDNHHDKEKLKPALEWEKEFIKFMKNYTENEMPSYMDIAYTSERSIEDELDRESQSDVSTILVSYFIMFAYIAISLGRFTTCSRLLIDSKVTLGLGGVLIVLASVVCSVGLFGFFGVAATLIIMEVIPFLVLAVGVDNIFILVQTSQREPRRPDETIAQHIGRTCILQQTLEKFCPDIAAGDVSCCDADQLKNFNANIGIALNLLNRCPTCVNNFLKHICALTCSPKQSEFLNPVKIEPYNATHQRITEVDYYLGATYMNVTFESCASVQMPSSNQLALDLMCGDYGAEFCTPQRLFDFMGDAADSLYVPFQINYISGDEPKDGFTPQNPSVLPCSVGLPGQPGCSCLDCLASCPAPPPAPPAPVPFTIAGADGYAVVMAIVFLIFSTLFLSGVYCCNQQENSVGVGSENNQEMTTNPTAVGWSIEQADGGEASFFEKLGADTETKLEDFFQWWGCIMASSPWIVLFFGLCFVVALGHGIKYMIVTTNPVELWASPNSRSRMEREYFDYHFRPFYRSEMLIISSKGLPDVEYKAPDGTVMQFGPVFNSQFLFDVLDLQNRIMGLGNETRIQDVCYAPMSSPFEGPVTPEQCGVMSVWGWWENNPDNVRDDLENNEYLSKILSCAQQVNLYFCDQIFFSIYIYIYIVWGGPVSPGVVLGGFLSPGEPLTKSSKFHRANALILTFLVDNHHDKEKLKPALEWEKEFIKFMKNYTENEMPSYMDIAYTSERSIEDELDRESQSDVSTILVSYFIMFAYIAISLGRFTTCSRLLIDSKVTLGLGGVLIVLASVVCSVGLFGFFGVAATLIIMEVIPFLVLAVGVDNIFILVQTSQREPRRPDETIAQHIGRTLGQVGPSMFLTSVSESVCFFLGALSDMPAVRAFALYAGAALLVDFLLQITCFVALLALDTRRQNDNRFDVFCCLSGAKSEAAEVAGEGGLYNLFRYVYVPFLMKREVRASVMIIFFAWLCSSVAVAPHIDIGLDQELSMPQDSFQTKYFQHLNKFLNMGLPVFFVVTEGLNYSDQNTQNMICGTRYCNDDSLSMQLYAASRISNVSYIAQPPNSWLDDFFEWSSLPSCCKRFPGNDSFCPNNYGPDKCQQCNIPLVGPEQRPALADFNHYLPFFLQDNPTPQCPKGGHAAYGRSVNYIANNKGISRVGATYYQAYHTVLKTSSDYYSAMRAARSIAANLTATLNRNANTTVNVFPYSVFYVFYEQYLTMWPDTLKSMGISVLSIFLVTFVLMGFDLFSALVVVITITMIVVNLGGLMYWWNISLNAVSLVNLVMAVGIAVEFCSHLVHSFSVFYFRMYLGIVLFGAAHGLIFLPVMLSYIGK-

Monarch geneset OGS2.0

Nucleotide sequence:

Protein sequence: