MonarchBase - Protein-coding gene

DPOGS201287
Transcript	DPOGS201287-TA	4029 bp
Protein	DPOGS201287-PA	1342 aa
Genomic position	DPSCF300176 - 544578-558995
RNAseq coverage	331x (Rank: top 35%)

Annotation
*Heliconius*	HMEL012403	81.89%
*Bombyx*	BGIBMGA003038-TA	82.83%
*Drosophila*	rok-PA	51.54%
EBI UniRef50	UniRef50_E3VQ36	82.83%	Rock1 n=7 Tax=Endopterygota RepID=E3VQ36_BOMMO
NCBI RefSeq	XP_974666.2	56.76%	PREDICTED: similar to rho-associated protein kinase 1 [Tribolium castaneum]
NCBI nr blastp	gi\|320202931	82.83%	Rho-associated protein kinase [Bombyx mori]
NCBI nr blastx	gi\|320202931	82.65%	Rho-associated protein kinase [Bombyx mori]

Group
Gene Ontology	GO:0005524	5.5e-93	ATP binding
	GO:0004674	5.5e-93	protein serine/threonine kinase activity
	GO:0006468	5.5e-93	protein phosphorylation
	GO:0016772	8.1e-83	transferase activity, transferring phosphorus-containing groups
	GO:0004672	5.8e-59	protein kinase activity
	GO:0005515	1.3e-15	protein binding
	GO:0000910	2e-11	cytokinesis
	GO:0004713	2.3e-08	protein tyrosine kinase activity
	GO:0035556	3.1e-08	intracellular signal transduction
KEGG pathway	nvi:100119770	0.0
	K04514 (ROCK)	maps->	Axon guidance
			Pathogenic Escherichia coli infection
			Regulation of actin cytoskeleton
			Shigellosis
			Chemokine signaling pathway
			Wnt signaling pathway
			Vascular smooth muscle contraction
			Leukocyte transendothelial migration
			TGF-beta signaling pathway
			Focal adhesion
InterPro domain	[78-340] IPR002290	5.5e-93	Serine/threonine-protein kinase domain
	[60-400] IPR011009	8.1e-83	Protein kinase-like domain
	[79-340] IPR017442	5.8e-59	Serine/threonine-protein kinase-like domain
	[1239-1262] IPR011993	1.3e-15	Pleckstrin homology-type
	[903-963] IPR015008	2e-11	Rho Binding
	[78-340] IPR020635	2.3e-08	Tyrosine-protein kinase, catalytic domain
	[1178-1231] IPR002219	3.1e-08	Protein kinase C-like, phorbol ester/diacylglycerol binding
	[343-403] IPR000961	6.4e-07	AGC-kinase, C-terminal
	[361-403] IPR017892	3.7e-06	Protein kinase, C-terminal
Orthology group	MCL11277		Multiple-copy universal gene

Nucleotide sequence:

>DPOGS201287-TA
ATGGAAGCAGTGAAGGATGAGGAGCGTTTGCTCCGTCTACGTGTCCTGGAGGAGAAAATATGTGATCCTCTATCAGTCGGCAACGTGGATGGTTTACTCGATACCGTCACCGCTCTCGTCTGCGACTGCTATTATCCGGCCATTCGACGGATGAAAAACGTTGAAGCTTATACAAGCAGATATGAAGAATTTGCTTCTGAGGTAGTTAATTTGCGTATGAAAGCAGCTGATTTTGATTTGATCAAAGTTATAGGCCGTGGGGCTTTCGGTGAGGTACAACTAGTCAGACACAAATCAACTCGTCATGTATATGCAATGAAACTGCTCAGTAAAGTAGAAATGATAAAAAGATCAGACTCTACATTTTTTTGGGAAGAAAGGCACATTATGGCCCATGCTAATTCAGAGTGGATACTGAAGCTTCATTTTGCTTTTCAAGATCAGAAATACCTCTATATGGTAATGGACTACATGCCGGGTGGAGACCTTGTCAGTCTCATGTCCAATTATGATATACCTGAGAAATGGGCAAAATTTTATACTATGGAAATAGTACTCGCATTAGATGTGATCCACGGAATGGGTTTCGTTCACAGAGATGTGAAGCCCGACAATATGTTAATTGATAAATATGGACATTTGAAGTTAGCAGATTTTGGAACCTGCATGAGAATGGGTCCTGATGGGCTTGTAAGAGCTAGCAATGCCGTTGGCACTCCCGACTACATTTCTCCTGAAGTGTTACAATCTCAAAATGGGGAAGGTGTTTATGGGCGTGAATGTGATTGGTGGGCTGTGGGTATATTTTTATATGAAATGTTAATAGGTGATCCACCATTTTATGCTGATAGTTTAGTTGGTACTTATGGGAAGATTATGGATCATAGAAATTCATTGCAATTCCCTGATGACGTTGAAATCTCGAAAGAGGCAAAGTCACTCATTCGAGGTTTGTTAACAGATAGAGTGAAACGACTAGGAAGAAATGATGTTGCGGAAATAAAGCAGCATCCTTTCTTTAAAAATGACCAGTGGAGTTTTGAAAATTTAAGAGATGCTGTACCGCCAGTCGTGCCCGAGTTGTCAAGTGATGATGATACGAGAAATTTCGATGATATCGAAAAATCGGATGCCTTGGACGAGTCTTTTCCAGAACCAAAGGCTTTTGTGGGTAATCATTTACCGTTTGTCGGCTTCACTTACAATGGTGATTATCAAATCTGCGGTGGAAGGAAAAAGGCTGCAGATGTCGTAGATACAATATCTAACAATCATATAAACAACGCAGGATCTGAAGCAATACTACATTTGGAAAAACTTTTAGAAAGGGAGAGAGATAGCAGACGTAAACTAGAAGACACACAAGTAATGTTGTGTGCACAGTTAGAAGAATTGTCTCAAAGGGAATCTAGGACTAAAAAAATTGCTGCAGATACAGACAAGGAGTTGGTTCTGCTGAAACGTGATCTCAAAGAAATACAACGAAAAGCCGAAATCGAAGCCGATTGCAGGCGGAACGCCGAGTTCAACTATAGTGACGTGAAGCGTCGGTTAGAAGAAGAACTCAACAAGAGAGCTAAAGAAATGAGTCATTTGCAAATATATAACGATAAAATTAATGTTTTAGAAAAAGAATTAAATGAAATGCGTGAGAAATTGAAACAGGAGTCTGAAGCTGCGGCTAAATCACGAAAACAAGCGGCCGAGCTTAGTGCAGCACAAGCAGCAGCGGCTGCTATGAGTGATGGTACTGTTGCCAGCCTACGAGCACAGAGGGACGTCCTTGAGAGAGATTGCAGCAATCTGTCCGAAGAGCTCGGTACAGTGAAGGCAGACAAGCAAAGAATGGAGGCAACACTAGCAGAAACAACCAGTCGGCTGACTGCAGCTCAAACAGAGCTTGAACGCTCGACCACGAGAATAAATCAGATAATAAATGACAACCGACAACTATCTGAACGAATATCTTCACTAGAAAAAGAGTGTGCTTCTATGGCACACGACCTGAAGGCCTCGCAGCACATGTATCAACAGGAAGTTCGGGCTCATCAAGAGACGCAACGGTCTCAGTTAGTTTCTAACCAGGAGGCTAACTTAGAGTTAGTTAAAGCCTTGCAAGTTAAATTGAACGGTGAGAAGGCGGCGCGCCATCGGGCCGAATGTCACACGCAGGATAAGGAACGCCAGATGTCCATGCTCAGTGTGGACTACAGACAGATGCAGCAGAGATTGCAGAAGCTCCAAGGAGAACATCGCCAGGAAAGCGAGAAGCTACACGCTGCCCGGGCCGCCCTGCATGACGCCTCGGAGAAACTGGCTGCTGCAGCCGCTGAAAGGGACATGCATTATTCAAGGAGCGAGGAGTTACGCTCCCAGCTGGAGAATGAACAGCATTACTGCGTCGTGTATCGGAACCAGGCGAACGAGGTGCGAGCTCAGCTGGACGAGCGGGAGCGATCAGCTCGCGATCTGGAACAGGAACGAGCCAGTCTCATGCATCAGCTGCAGCTTGCCATCGCCAGGGCTGATTCGGAGGCGATCGCCAGGTCTATAGCAGAGGAGACGGTCGGAGAGTTGGAGAAAGAGAAGACGATGAAGGAGTTGGAGATGAGGGACGCTCTGGCGCAGCACCGCGGCGAGCTGGCGGCCAGGGACGCGCTGGTGCAGGGCCTGAGGGACAGAGACCACGAGAACAGAGCCACCATAGACCTGCAACGCAAGGAGGTGGACGAGCTTAGACGCAGCGGCACCGCGCTGGCCGAACGAGTGGCGACGCTGCAGAGACTACAGGACGACGTCGACCGGCTTAACAAGAAACTCAACTCGGAGATCATGCTCAAACAACAGGCCGTCAATAAACTGGCCGAGATTATGAACAGGAAAGACATGAATCCAGCGTCCACCAAGAACAAGAGCAAGATGTCAGTGCGCAAGGACAAGGACTACCGCAAGCTGCAACAGGAACTGACCAGGGAGAAGGAGAAGTTCGACCAGCACATCTGCAAGCTGCACAGAGACCTGCAGGAGGCGCAGCAACAGATACTGGAGGAGCAACAGACGAAGCTGCGACTGGCCATGGAGGTCGACAGCAAGGACGCGGAGATCGAACAGTTGAAAGAGAAACTGGCGGCGCTGACGAGTGAGACGGCCTCGCAGTCCTCCGCGGACGCAGAGGACGGCGACACGGAGCAGACGCTGGAGGGCTGGCTGTCCGTGCCCTTCAAACAGAACATACGGCGGCACGGCTGGAAGAAGCAATACGTGGTGGTCTCCTCCAAGAAGATCATATTCTACAACTCGGAGAACGACAAGCAGAACACCACCGACCCCGTCATGATCCTCGACCTGAGCAAAGTGTTTCACGTGCGGTCAGTGACCCAGGGTGACGTCATCCGCGCCGATGCTAAGGACATTCCTCGCATCTTCCAGCTGCTGTACGCTGGTGAGGGCGAGGCTCGTCGGCCGGGAGACGCTCAGGACACGCCCACTGACGGGCCAGACCATGCTGGTAACACGGTCCAACACAAGGGTCACGACCTGGTCAGCATCACGTACCACATCCCCACGGCCTGCGAGGTCTGCACCAGGCCTCTGTGGAACATGTTCCGTCCGCCGCAGGCCTACGAGTGTAGACGTTGTCGTATGAAGATCCACGTGGAGCACGTGTCGGAGGGCGAGGGCGTGGCGGCCTGCAAGTTACACGCGGACCGGGCGCGGGAACTGTTGCTACTGGCGGCCGGCGCGCCCGAACAGAGGCGGTGGGTGGCGAGACTAGCCCGCCGCGTCCAGAGGCACGGCTACCGAGCGGCCATCACCAACAACCATGAAAACAATAAGCTGTCACCCAGGGAAATGCGTACCTTGCGTTTATTAGTTCGGTTGATGTTCTTTGTGGCGGGACTCGATGCGTTCAAACCTGAAGCCGGGATATCTGAACGCGTCACAGCGCAGTTCAACCCTGCCAGCGAACGCCTCCCTTCCTCGCCAGTGACTTCCATCCGCTACACTCCCCGCACTGCGGATGTTTGA

Protein sequence:

>DPOGS201287-PA
MEAVKDEERLLRLRVLEEKICDPLSVGNVDGLLDTVTALVCDCYYPAIRRMKNVEAYTSRYEEFASEVVNLRMKAADFDLIKVIGRGAFGEVQLVRHKSTRHVYAMKLLSKVEMIKRSDSTFFWEERHIMAHANSEWILKLHFAFQDQKYLYMVMDYMPGGDLVSLMSNYDIPEKWAKFYTMEIVLALDVIHGMGFVHRDVKPDNMLIDKYGHLKLADFGTCMRMGPDGLVRASNAVGTPDYISPEVLQSQNGEGVYGRECDWWAVGIFLYEMLIGDPPFYADSLVGTYGKIMDHRNSLQFPDDVEISKEAKSLIRGLLTDRVKRLGRNDVAEIKQHPFFKNDQWSFENLRDAVPPVVPELSSDDDTRNFDDIEKSDALDESFPEPKAFVGNHLPFVGFTYNGDYQICGGRKKAADVVDTISNNHINNAGSEAILHLEKLLERERDSRRKLEDTQVMLCAQLEELSQRESRTKKIAADTDKELVLLKRDLKEIQRKAEIEADCRRNAEFNYSDVKRRLEEELNKRAKEMSHLQIYNDKINVLEKELNEMREKLKQESEAAAKSRKQAAELSAAQAAAAAMSDGTVASLRAQRDVLERDCSNLSEELGTVKADKQRMEATLAETTSRLTAAQTELERSTTRINQIINDNRQLSERISSLEKECASMAHDLKASQHMYQQEVRAHQETQRSQLVSNQEANLELVKALQVKLNGEKAARHRAECHTQDKERQMSMLSVDYRQMQQRLQKLQGEHRQESEKLHAARAALHDASEKLAAAAAERDMHYSRSEELRSQLENEQHYCVVYRNQANEVRAQLDERERSARDLEQERASLMHQLQLAIARADSEAIARSIAEETVGELEKEKTMKELEMRDALAQHRGELAARDALVQGLRDRDHENRATIDLQRKEVDELRRSGTALAERVATLQRLQDDVDRLNKKLNSEIMLKQQAVNKLAEIMNRKDMNPASTKNKSKMSVRKDKDYRKLQQELTREKEKFDQHICKLHRDLQEAQQQILEEQQTKLRLAMEVDSKDAEIEQLKEKLAALTSETASQSSADAEDGDTEQTLEGWLSVPFKQNIRRHGWKKQYVVVSSKKIIFYNSENDKQNTTDPVMILDLSKVFHVRSVTQGDVIRADAKDIPRIFQLLYAGEGEARRPGDAQDTPTDGPDHAGNTVQHKGHDLVSITYHIPTACEVCTRPLWNMFRPPQAYECRRCRMKIHVEHVSEGEGVAACKLHADRARELLLLAAGAPEQRRWVARLARRVQRHGYRAAITNNHENNKLSPREMRTLRLLVRLMFFVAGLDAFKPEAGISERVTAQFNPASERLPSSPVTSIRYTPRTADV-

Monarch geneset OGS2.0

Nucleotide sequence:

Protein sequence: