| DPOGS203453 | ||
|---|---|---|
| Transcript | DPOGS203453-TA | 4407 bp |
| Protein | DPOGS203453-PA | 1468 aa |
| Genomic position | DPSCF300242 + 180239-193540 | |
| RNAseq coverage | 401x (Rank: top 30%) | |
| Annotation | ||||
|---|---|---|---|---|
| Heliconius | HMEL015026 | 0.0 | 68.98% | |
| Bombyx | BGIBMGA011102-TA | 0.0 | 63.07% | |
| Drosophila | Sos-PA | 0.0 | 51.99% | |
| EBI UniRef50 | UniRef50_E0VPV8 | 0.0 | 54.24% | Histone H2A n=10 Tax=Eumetazoa RepID=E0VPV8_PEDHC |
| NCBI RefSeq | XP_002428152.1 | 0.0 | 54.24% | ras GTP exchange factor, son of sevenless, putative [Pediculus humanus corporis] |
| NCBI nr blastp | gi|242014971 | 0.0 | 54.24% | ras GTP exchange factor, son of sevenless, putative [Pediculus humanus corporis] |
| NCBI nr blastx | gi|242014971 | 0.0 | 49.26% | ras GTP exchange factor, son of sevenless, putative [Pediculus humanus corporis] |
| Group | ||||
|---|---|---|---|---|
| Gene Ontology | GO:0007264 | 1.5e-261 | small GTPase mediated signal transduction | |
| GO:0005622 | 1.5e-261 | intracellular | ||
| GO:0005085 | 1.5e-261 | guanyl-nucleotide exchange factor activity | ||
| GO:0035023 | 1.1e-35 | regulation of Rho protein signal transduction | ||
| GO:0005089 | 1.1e-35 | Rho guanyl-nucleotide exchange factor activity | ||
| GO:0003677 | 1.2e-34 | DNA binding | ||
| GO:0051056 | 1.6e-32 | regulation of small GTPase mediated signal transduction | ||
| GO:0005515 | 1.2e-19 | protein binding | ||
| KEGG pathway | phu:Phum_PHUM366140 | 0.0 | ||
| K03099 (SOS) | maps-> | Prostate cancer | ||
| Regulation of actin cytoskeleton | ||||
| Fc epsilon RI signaling pathway | ||||
| MAPK signaling pathway | ||||
| Gap junction | ||||
| Dorso-ventral axis formation | ||||
| Glioma | ||||
| B cell receptor signaling pathway | ||||
| Pathways in cancer | ||||
| Chemokine signaling pathway | ||||
| Endometrial cancer | ||||
| Natural killer cell mediated cytotoxicity | ||||
| Insulin signaling pathway | ||||
| Neurotrophin signaling pathway | ||||
| T cell receptor signaling pathway | ||||
| Focal adhesion | ||||
| ErbB signaling pathway | ||||
| MAPK signaling pathway - fly | ||||
| GnRH signaling pathway | ||||
| Renal cell carcinoma | ||||
| Acute myeloid leukemia | ||||
| Non-small cell lung cancer | ||||
| Jak-STAT signaling pathway | ||||
| Chronic myeloid leukemia | ||||
| InterPro domain | [27-1269] IPR008937 | 1.5e-261 | Ras guanine nucleotide exchange factor | |
| [27-1269] IPR015759 | 1.5e-261 | Ras GTP exchange factor, son of sevenless | ||
| [573-1106] IPR023578 | 1.9e-113 | Ras guanine nucleotide exchange factor, domain | ||
| [838-1080] IPR001895 | 4.8e-74 | Guanine-nucleotide dissociation stimulator CDC25 | ||
| [212-434] IPR000219 | 1.1e-35 | Dbl homology (DH) domain | ||
| [9-184] IPR009072 | 1.2e-34 | Histone-fold | ||
| [600-797] IPR000651 | 1.6e-32 | Ras-like guanine nucleotide exchange factor, N-terminal | ||
| [435-549] IPR011993 | 1.2e-19 | Pleckstrin homology-type | ||
| [445-555] IPR001849 | 6e-07 | Pleckstrin homology domain | ||
| Orthology group | MCL11388 | Multiple-copy universal gene | ||
| Genotypes for resequenced monarchs and outgroup Danaus species |
|---|
>DPOGS203453-TA
ATGCTGCCCACAGTGGAGGAGACTCGGGGTTACGACTTCCAGGACCCGGAGAATGCGGAGAAATGGAAGGGCTTCTTCATCAGCTCTCTCCGCAAGGTGCTGGAGTCGGTCCACCCCACGCTGACGGCGGACGAGGGCGCTCTGGAGTTTGTGGAGTCGCTGTGTCTTCGTCTGCTGGGCATGCTGTGTGCGCCGCCCGCGCCTCTCAGCGTGGCGGATGGAGAGGAGAGGGTGGCCCGCAGCTTCCCCACGCCACTGGACCGTTGGGCGCTCATCGAGGCCAGGGAGGCGGCCGGCGCCAGGAGACGGAAACTACTGCTGCCACTTGAAAGGCTGCATCTGTTGCTGCAGAAGGAGGTGTTGCTCTATAAGATCGACATGTCGGTGACAACCTTCATGACCGTCATTCTGGAGTTCATCAGCACCGACATCCTGCGGCTGGCGGGGAACTTCGTGAAGAAGATTTCCCAGAAGAGCGGCTACCAGGTCATCACCTGCAGTGACATCAAGACTGCCATGTGCGCTGATAAGGTCCTGATCGACATGTTCTACCAAGACTCGGAGCTGGCCAGCATCGCAGCTCTACCGGCGTTCAACACAAGCGAAAGGGGAAGGAGAGCGTCGCTGTCGTACGGGGATCTCGTGCGGGACCTGCTGGCTGACGAGCGGAACTTCCTTAGGGACCTCAACCTCATGATACGGGTGTTCAAGGAGGAGCTAGAGAAGATCGTCGATGACAATAAGGTGATATCTCTAATATTTGGCAACATAGTGGACATATACGAGCTGACGGTCACGCTGCTGGGCAACCTCGAGGACGCCATGGAGATGTCCCAGGACACGCTCACACCATACATCGGCAGCTGTTTTGAAGAACTGGCGGAGGTGGAGGAGTTCCGGGCGTTCGTCCGCTACGCCAACATCGTCACCAGGAGGGAGTCCCGGGACGCACTCGCCGCGCTCGTTGATGATCCACAGCTGGGCGAGCGCCTGGAGACGGCTGGCCACGGGTTCCGCCTGGCCGTCAAGTACTGCCTGCCGCGGCTGCTGCTGTCTCCGGTGGCGCACGTGTTCGTGTATCACTCGTACGTGCTGGCCATGCTGCCCCTGGCGCCCGCTAGCGACGACCGGGAGAGCTTCAAACAGGTCGAATGCAATCTACATCCAATAGAGAAATTACTGACAAGAGCCTTGGGGAACGGACCGCAGCTGGACGGCGCGATGAGGTCGGCGTCTCGAGCTCGCCGGAAGATGGCCATCGACAAGTGTAACGAGCTGGCCAGGCTGGTCGACAACTGGGACGCCAGGGACGTGCCGCAGTGCTGCAACGAGTTCATTAGAGAGGACACGCTCACCAAGCTGGGTCCGGGGAAGCGCGTCGCTGAGCGGAGAGCTTTTTTATTCGACGGACTCCTGTTGCTCTGCAAACCCGTCACCAGCCTGGTGACTGTGAACAGCGGCGTGACGGCGGGCCCGCCCCAGCTGAAGCTGAAGGAGAAGCTGCACATACGGAAACTGGACATAGTGGACCGCCCCGACGGAGAAGAGGGTCGCAATCTAATGGAGCTGTGTCCGCGCGTGGGCCCGCCCGTGGTGCTGGCGGCCTCGTCTCCCGCCGAGAAGAGATGCTGGATGAGCGACCTCGTCATACTCAACACCAAACCCATGCTGGACAGGAGTCTGGACAGTATTCTCCTGGACCTGGAGCGTCGTCACCCTCTCCGCCTGCCGAGCCCCTCCTTGTACCGGTTCGCGGAGCCCGACGGACCTCACAATATACTGCTGGAGCACGGACACGGTCCCGCGCCCCTCATCAAGGGCGCGACGCTGCTGAAGCTGGTGGAGCGCCTCACGTACCACGTGCACGCCGACCTCAACCTGGTGCGGACCTTCCTCACCACCTACCGCTCCTTCTGTTCACCCTCGGAGCTGCTCGCTTTACTCATCGAGCGCTTCGACATACCCGAACCGCACCTCGTGTACGACGCGCCTCGACCCGTCCCAAGGATCAAGATCCCCAGGAAGGACATCAGTCCCAACGCTTCGCTGATGGACCTCGACCTCGACATCGGTAACATTATACTATACAGAGTAGACCTTGTAGAGACGTGGCTGAGAGCGGATTGCGTGGAGATCTCGGCCACCAGTGACGCGGAGAAGCTGAGCAAAAACACGGCCAGGGAGGACTGGAAGAGATACAGGAAGGAGTTCCAACAACCCGTGAAGTTCAGGGTGATAAACGTCCTCCGACACTGGGTGGATCAACACTTCTATGACTTCGAGCGCGAGCCGGAGCTGCTCGCCAAGCTGAAGAGCTTCCTGGAGGCCGTGGACGGCAAACCCATGAGGAAGTGGGTGCAGAGCGTGCTCAAGACCGTTCAGAGGAAGAGCGGCCTACAGTCGGACAACGAGTCCTTGTGTAGCGTGTCGTCGGGCGTGTCGTACGTGTTCGACAGACTGCCGCCGGCGCCGCTCAGGCACGTGGCGGAGCCCGACAGGCACGACTGGCATCCGCTGGCGCTGCACCCGCTGGAGGTGGCCCGCCAACTCACGCTCCTCGAGTTCCAGCTATACAGACAGGTGAAGCCGTCGGAGCTGGTGGGGGCGGCGTGGACCAAGAAAGACAAGGAGAAGTCCAGCCCCAACCTGTTCAGGATCAGCAAAAACACCACCAACTTCACTCGCTGGATAGAGAAGTGGATAGTGGAGAGTGAGAACGTGGAAGAGCGCGCGGGCGTGCTCAGCTGGTGTCTGGAGCTGGCCGTGGCGCTCAGCGACCTCAACAACTTCAACGGCGTGTTCGCTGTGGTCGCCGCCTGCGAGTCCGCCTCCGTCTACAGGCTCAAGTACACCTTCCAGATGCTGCCGCCCCGCCTCCTGCGCGCTCTAGACCAGTTCCGTGAGCTGAGCTCGGACCACTTCCGCCTGTACCAGGAGAGACTGCGGAGCATCAACCCGCCCTGCGTGCCCTTCGTGGGGGTCTACCTCACCAAGATACTACACATCGAGGAGGGGAATCCCGATTTCCTCTCCAACACCGAGCTCATAAACTTCTCGAAGCGTCGTATGGTGGCGGAGATAACCGGCGAGATCCAGCAGTACCAGAACCAGCCCTACTGTCTGACGCTGGAGCCCAGGACCAGGGCTTTCCTGGAGAACCTGGATCCGTTCCCCGGGATGGATGATAACGAAGTTACCAACTACCTGTATGGAAAGAGCAAGGAGATCGAACCCAAGGGAGCCGTCAAACAGACGCACAAGTTTCCCCGCCGCTACCCCGAGCTGTCTCTGAAGCCGGTGAAGGTGTCGCGCCGCAGACACGACACGTCCTCCACCACGCTCTCCTCCACCAACTCGCTCGTCAGTCTGGACGGAGCGTTCAGCGTGTCCCAGCTGTCGCCCACCAGCAGCGTCTGGGACGGAGCCAGCGTCGCCTCCCTGCCGCTCCACGCCCACGACCAGGGGAGCAGGGAGGAGCGCTCGGTGACCAGTCCGCGGCTGGAGAGAGCCAGCTCCAGCTCACTGGCGCAGCTCGGGCAGCTCAGTCTGCTGGACAAGCTGTTCGACAAGAGCAAGTCCGCCGCCACGCTGCACAGGAACAGCGGCTCCACCAAGGACGACCCGCCCTCGCCGCGCGACAACCACTCACCCAAGCGTCGGCCGGCGCTGTCTCCCCGCGGCGCGCTCGTGGAGGCGGACATGTACCAGAACAGAAGACGCACGGACACACAGGAGCGTGTGCCGCCGCTGCTGCCGCGCGGGGGGGCCGACCCCGAGGCGCCGCCCGTACTGCCGCGGAGACCGCCCTCGCCGCACACGGCGTCGACGGAGCCGCCCCCGGAGCCCCCCGACCGCCCGCTGCCGAGCCCCAAGCACCACGACCTGTTCAGACACGGGGAACTGGCCGCGTGCACGTTGATCAGAAACAGCTATAAGATAAATACATTGATCTGTTACAAACGACCAATAACCCCTGACCCGCAGGAGTCCCGCGCTGTCCCCGGCCGCCCCGCCCGCGCCCAGCCCCATGATGGTGGACAGGTGAGACACACACCCTGTATACAGTGCGAGATATATAATGAACACTCCTTGGCCCGAGCGGGACCAGACCCTGTGACCTGGCGGCCTTCAGCTTCCCCTCGGCCACGTCTCCCGGACACATCCCCGGTGAGTGATCCTGTTACTACACACCCCTCACCCCCTCACACCTCACCCTTGATATTAACGGAGCATGTGTCGCCCCCAGCGGAGACCGTCCCCCCGCCCCTGCCGCCGCGGAGAAGAAGAGACTCCGCCGCGCCCCACACGCCGCACCCGGTTAGCTCCAAAACTCCCGCCGAAGCCGGCCGCGGCGGCCGTCGCCCCGCGGACCTAGGACGCCAACGGACACGCAAGCTGCCAAACTAA
>DPOGS203453-PA
MLPTVEETRGYDFQDPENAEKWKGFFISSLRKVLESVHPTLTADEGALEFVESLCLRLLGMLCAPPAPLSVADGEERVARSFPTPLDRWALIEAREAAGARRRKLLLPLERLHLLLQKEVLLYKIDMSVTTFMTVILEFISTDILRLAGNFVKKISQKSGYQVITCSDIKTAMCADKVLIDMFYQDSELASIAALPAFNTSERGRRASLSYGDLVRDLLADERNFLRDLNLMIRVFKEELEKIVDDNKVISLIFGNIVDIYELTVTLLGNLEDAMEMSQDTLTPYIGSCFEELAEVEEFRAFVRYANIVTRRESRDALAALVDDPQLGERLETAGHGFRLAVKYCLPRLLLSPVAHVFVYHSYVLAMLPLAPASDDRESFKQVECNLHPIEKLLTRALGNGPQLDGAMRSASRARRKMAIDKCNELARLVDNWDARDVPQCCNEFIREDTLTKLGPGKRVAERRAFLFDGLLLLCKPVTSLVTVNSGVTAGPPQLKLKEKLHIRKLDIVDRPDGEEGRNLMELCPRVGPPVVLAASSPAEKRCWMSDLVILNTKPMLDRSLDSILLDLERRHPLRLPSPSLYRFAEPDGPHNILLEHGHGPAPLIKGATLLKLVERLTYHVHADLNLVRTFLTTYRSFCSPSELLALLIERFDIPEPHLVYDAPRPVPRIKIPRKDISPNASLMDLDLDIGNIILYRVDLVETWLRADCVEISATSDAEKLSKNTAREDWKRYRKEFQQPVKFRVINVLRHWVDQHFYDFEREPELLAKLKSFLEAVDGKPMRKWVQSVLKTVQRKSGLQSDNESLCSVSSGVSYVFDRLPPAPLRHVAEPDRHDWHPLALHPLEVARQLTLLEFQLYRQVKPSELVGAAWTKKDKEKSSPNLFRISKNTTNFTRWIEKWIVESENVEERAGVLSWCLELAVALSDLNNFNGVFAVVAACESASVYRLKYTFQMLPPRLLRALDQFRELSSDHFRLYQERLRSINPPCVPFVGVYLTKILHIEEGNPDFLSNTELINFSKRRMVAEITGEIQQYQNQPYCLTLEPRTRAFLENLDPFPGMDDNEVTNYLYGKSKEIEPKGAVKQTHKFPRRYPELSLKPVKVSRRRHDTSSTTLSSTNSLVSLDGAFSVSQLSPTSSVWDGASVASLPLHAHDQGSREERSVTSPRLERASSSSLAQLGQLSLLDKLFDKSKSAATLHRNSGSTKDDPPSPRDNHSPKRRPALSPRGALVEADMYQNRRRTDTQERVPPLLPRGGADPEAPPVLPRRPPSPHTASTEPPPEPPDRPLPSPKHHDLFRHGELAACTLIRNSYKINTLICYKRPITPDPQESRAVPGRPARAQPHDGGQVRHTPCIQCEIYNEHSLARAGPDPVTWRPSASPRPRLPDTSPVSDPVTTHPSPPHTSPLILTEHVSPPAETVPPPLPPRRRRDSAAPHTPHPVSSKTPAEAGRGGRRPADLGRQRTRKLPN-