MonarchBase - Protein-coding gene

DPOGS205284
Transcript	DPOGS205284-TA	4452 bp
Protein	DPOGS205284-PA	1483 aa
Genomic position	DPSCF300021 + 409718-420083
RNAseq coverage	184x (Rank: top 49%)

Annotation
*Heliconius*	HMEL017486	0.0	57.40%
*Bombyx*	BGIBMGA011028-TA	0.0	44.05%
*Drosophila*	Ark-PB	2e-26	24.79%
EBI UniRef50	UniRef50_E3VQ35	0.0	44.05%	Apaf-1 n=1 Tax=Bombyx mori RepID=E3VQ35_BOMMO
NCBI RefSeq	NP_001186937.1	0.0	44.05%	Apaf-1 protein [Bombyx mori]
NCBI nr blastp	gi\|317108135	0.0	44.05%	Apaf-1 protein [Bombyx mori]
NCBI nr blastx	gi\|317108135	0.0	44.33%	Apaf-1 protein [Bombyx mori]

Group
Gene Ontology	GO:0005524	9.7e-31	ATP binding
	GO:0006915	9.7e-31	apoptosis
	GO:0005515	4.8e-19	protein binding
	GO:0005622	1.9e-14	intracellular
	GO:0042981	1.9e-14	regulation of apoptosis
KEGG pathway	oaa:100073402	2e-56
	K02084 (APAF1)	maps->	Small cell lung cancer
			Huntington's disease
			Amyotrophic lateral sclerosis (ALS)
			Alzheimer's disease
			p53 signaling pathway
			Parkinson's disease
			Apoptosis
InterPro domain	[134-418] IPR002182	9.7e-31	NB-ARC
	[778-1331] IPR011047	1.9e-23	Quinonprotein alcohol dehydrogenase-like
	[1044-1125] IPR015943	4.8e-19	WD40/YVTN repeat-like-containing domain
	[1-93] IPR011029	3.7e-17	DEATH-like
	[8-87] IPR001315	1.9e-14	Caspase Recruitment
Orthology group	MCL18368		Patchy

Nucleotide sequence:

>DPOGS205284-TA
ATGGATATCAAGAAGCGGATGCTATTGCAACACCACATGCAGGATATCGTCAAAGATCTAGACGTTAATCACATACTTGATGAACTGTTCACGAAAAATGTCATATCCAACGAGGATTTCGATCACATATACAACTTGCCGGATAGGGTAGAACGTGCTAGATTTCTCATAGGCATTATACTGACCAGCAATAATAATGCATATGAAGCTTTCGTGGGTAGCTTGCAAAAGGATTACAAATGGTTGTATGAAAAGTTGTCAGTAGAAAACAACCAAGCCATGATAGAAGATAGCTTCGAAGACTGTCTAAGTAGGGGGGATGTGCCGCGGCTGCCAGATCACTTTATCAGTAGAGCTTCTTTGGAAAGGGAATTACATTCTAAATTAAAAATCCTTTCGCGTCATAAGATCCTGGTTCTCTATGGGATGCCAGGTTGTGGTAAAACGGTGTTGGCTATCAGCGTTCTGAGGAAAGAATCAACGCTCATCATGAACGACTTCAACGGCGTTGTATTCTGGCTCAACCTTAGCAACTGTAAGACTGAAGACGATGTCATTGCTCAACAGAACAGGTTATACCGCAAGGCGTCGCTAATGTTCAACCAGAATTCGTTCATGAATTCATCGATGTCTCTATCCAGTGCGTGTTCAAGAGGAGATTCGTTATCTAATTATGATCATACCAGTGAGGAATTGAAGCATAACTTAAAACTGCAATTTTCCGGAGAGCCCTTGAAGGAGGCCTTGCTGGTGTTGGACGAAGTCAATGAAAAGAACATTCTAGAAGCTTTCGATATCGGCTGCAAAATACTCGTAACTACTAGAGACAGAGAAGTCTTCGTCAACTTTGATTCCCAGATTGTAGAAGTAGAAAATCACTTTTCTGAGACGGAATCATTAGAGTTGTTTGCTTCGTGTCTTGGTGTAGAGGCTGCGAAGCTACCCAGACAAGCGAAGAAGTTACACGAAGTTTGTAAAGGAAGTCCATTTCATATAGCATTGATTGTGGCTGAACTAGCCGAAAATAAAGAACGTCTGATAAACGACCCGCAGAGGTGGAATTATTATATTGATAAGCTGAGAAAAAAGGAACTTTTCTCTCTACCGAGACGAGAGAAACCAATGAAGACCGTCGAAGTGTGCATTAACTTGCTCAAACCGGAAATGCTGGCGTTATTCAAGATGCTAACAATATTGCCATACAACACTAAGATATCAACTAAAGTACTCAGCAGACTGTGGAACAAAAGCATAATAGAAGTTGAGAGCATAACGAAACAGCTGAGAAGTAAATCATTGATCATGGAGTTCTACGACAGGGACCAAAAGAATTACACCTACGAAATACACGACTTGATCATGAGCTATCTCATATCGAGTTCCAACGACGACGAAGTTAGGAATATGCACCTGAATTTCCTCAGAAACTATGATTACGATGTCTCGAACGGCGTGCCTGTAGAAATAGCCGATGACGGATACATAGCGTTCCACATCGGTTACCATTTAGCCAAAACGAGAAACGCAGGCAATATGTGGGATTTGTTCAATAAACTGTATCTAGATTTGAGATTTTTAGGTAACAAAGTCAGACTAACCGGCTCAGCTGATGTTATATTGGATTTGGAAACTTACGAAAAGTATATTACGAAAAATTGTGAGCTCGATACAAGACTATTATACAGTATCAAAGAATTTCTCATAAGACACGGAACGGATCTCTACAGGTATCCATGCACGGATATAGTACAAAGTATACTACAGAACGAAAGCAAGGGAATCCTCTATACTAAAGCCAGTCAGATCGCTAAAGAGAGATGCGCGAAAAACGAACTGTACTTTGAGTTTTTACACGAACAAAATGTAGAAGAAATCAAACATTCCACAATAGATGTGAAGGAGAAAATAACTTGTGTGTGCTTCTTCTTCAAATATGTTCTGATTGGAACTGCCACAGGGGCTATTAAGCTGTTCGAGCTGAACACCAACAAGCTAGTGCGCTCTCTCCAGCTGCAATCTTCAGTACGTGCGATGTCTCCGCGCCTATCGTCCCCTGCAGCGCTTGCAGCGCTAGAACACAGCGGTGTGTTGCGGCTGTGGTACGACCTGCAGCCGGAAAGTGATCACGACAGTGACGTCATCGAAGAAGAATGTGAAGAAAGCTTCAACAATAACTACCTTACCAACAAAACAATACAACCCAAACTGGGACCGTTTCTGAACTGCCGCTGGGCAAATGACTTCCTAGTAACACACACTTCAGAAATAATCATAATATATTCAATAAACGCTGAGGTACTTCATATCCTGTGCTGTATTCCATGTAACTTTGATAAAAACGTTATATTCGCAACGCCGCGGAATCTAGAAATCGTCAATTTGAAGACTAAAGAGAAACAAGTCTTTGAAACAACGGACATCGTTTTAAACATCCTGACTGTACCCGGCAGTAACAGAATTCTTACCTTAAATGAAAATGAAGTCACAGAATACGAATTCAAAATGTCTTTCAAACACAAAGAGAACAGGAGAGGAAAGACTGTCGTTTCAAGCAACGCTGTTAAAGAGAACATATTATTTATATCGATGGCCGTCAACAACACCGGCACGCTGCTGTTCGTGTCAACAAACGACAACAGAATTATTTGTGTCGATCTAAAAACGAATTCATATATATTTGATCTACAGAATAGGAGAGGGAACGTGACATGTATGTCTGTATGCGAGGTGTCCGAGCCTGAATACTTAGAAGGATCGGATCTGTTGTTGACTGGCTCCGGACAACACGAGGACACCGCGAAGGTTTGGTACATGGAAGCTGGCTACGTCGCCGCTAACACTCATAGGAATAGCAAAGCTCGTCTAACAACTAAATTCGACGCTAATTTTGTAGCTGTATCGACACCGAACGATACTTCAACCAACAGTTCCACAACGACGCCGAAGAGACATCATTCGTTTGCGAACCAACACGAGGTTGTCAAAAAAGTTGTCAAAACCACCATGAGCCTTGACAGGCATACGCTGAAACCGTTGAACTTGGATGGGATTTGTAACGGCATTAGCAGCAATGGGATGCAACCCTTATTGGCGATTGTTGATGACAAAAATAACATACAGATAATGCGTGGCAGGAAGCTCATAGCAGAGATATCTTCTTATTCAGACCAACAGGTCACAGCGGTTCGTATATCGCCGTGCAACCACTACGTTATATACGGACTCAGTTCCGGTATTGTGAAGAAATTTATCGTTCGCTCCAAGGAGACCAAGGATATAATGGACGTGAACAGCCCCGTGATGTATATGAGCTTTGTTAACAGCAACATGTTGATAGTGGCCGGGGAGAACAAATGTCTGATGGCCTATAGACTCACTGACAACGGTGAATGGGAACCGCTCATGCTGATGAGGGGTAACACTGATCTAGGATCGCAGGAACTATTGAATGATATACAAGGAGTTAAAAAGAAACCGCAACAGTTGTCAAGTATAGACAGCGAGAGCAGTATCAACTCAAGGGAGTTTTACTTCAATTCCGTCACATCAAAGCTCTGCAAGGGAAGTAGTTTGGTGGACTGTTACTGGATACAAGGCATGGGCCTTGTCACCATAGAGTCAAACGCAACCATCAAGCTGTGGGACGAAAACCTGGAGTTAGACAAAGTGTTGCACGGAAAACAAACAGCCCCCATACAGAGCAAAGACGTACGACTGTGTTGTTCCGATTACAAGAAGAATATACTGGTCATATGTGACTATTCCAATGAGTGTTTTCAGACATTCGAAGTCAGACACGGACAAATGAATCTGATACAAGAATACGAACTCAAGAAAAAGATATACTCATGTGCTCTCACAGATGACGGAAATATACTGGCGCTGGGACTTGAATCAGGGGATGTTGTGCTATGGAGCGTGGCGAACAAACGTTTGCTGGAGGTGTTGAAGCATCATTCGTCGCGGGTCCAGTGTTGTTGTTTCTCTCCGGTGCCATATAGACGCGGCCGGCCGGGAGCGCTCTCCCCCGCGGGGACCCCCGGGGACGACGAGCCGCCTCTAGTACTAGTGACCATGACAGCTGATGTAGTATGGTGGGATGTCAGCTATATCATACGGAGAAGACTCAATAGGAACTTGAGAACGGGCAGAACCATACTCACACCTCTACCAAGTCCAATGGAATTCAAAAATGAAATACAATCAGACGATAACGCCAACAAGAATAACTATTTCTTCAACGATAACTTACTGAATCCAACGCAAATGTGGAAAGCTAATTGGAAACATAAAACATATAAAGAGGGTTCAAAGAGGAAGGAAATCCTTGCGTGTATCAAGCTATCAGGGATGAACGCCAAGAAGATCTGCCACGATGAAAAGTTCTCCTGTTTCGTGACAGTCGACAACCCTGGCCTTATATACATTATGACGCTTATGGGTTCCGTTTAG

Protein sequence:

>DPOGS205284-PA
MDIKKRMLLQHHMQDIVKDLDVNHILDELFTKNVISNEDFDHIYNLPDRVERARFLIGIILTSNNNAYEAFVGSLQKDYKWLYEKLSVENNQAMIEDSFEDCLSRGDVPRLPDHFISRASLERELHSKLKILSRHKILVLYGMPGCGKTVLAISVLRKESTLIMNDFNGVVFWLNLSNCKTEDDVIAQQNRLYRKASLMFNQNSFMNSSMSLSSACSRGDSLSNYDHTSEELKHNLKLQFSGEPLKEALLVLDEVNEKNILEAFDIGCKILVTTRDREVFVNFDSQIVEVENHFSETESLELFASCLGVEAAKLPRQAKKLHEVCKGSPFHIALIVAELAENKERLINDPQRWNYYIDKLRKKELFSLPRREKPMKTVEVCINLLKPEMLALFKMLTILPYNTKISTKVLSRLWNKSIIEVESITKQLRSKSLIMEFYDRDQKNYTYEIHDLIMSYLISSSNDDEVRNMHLNFLRNYDYDVSNGVPVEIADDGYIAFHIGYHLAKTRNAGNMWDLFNKLYLDLRFLGNKVRLTGSADVILDLETYEKYITKNCELDTRLLYSIKEFLIRHGTDLYRYPCTDIVQSILQNESKGILYTKASQIAKERCAKNELYFEFLHEQNVEEIKHSTIDVKEKITCVCFFFKYVLIGTATGAIKLFELNTNKLVRSLQLQSSVRAMSPRLSSPAALAALEHSGVLRLWYDLQPESDHDSDVIEEECEESFNNNYLTNKTIQPKLGPFLNCRWANDFLVTHTSEIIIIYSINAEVLHILCCIPCNFDKNVIFATPRNLEIVNLKTKEKQVFETTDIVLNILTVPGSNRILTLNENEVTEYEFKMSFKHKENRRGKTVVSSNAVKENILFISMAVNNTGTLLFVSTNDNRIICVDLKTNSYIFDLQNRRGNVTCMSVCEVSEPEYLEGSDLLLTGSGQHEDTAKVWYMEAGYVAANTHRNSKARLTTKFDANFVAVSTPNDTSTNSSTTTPKRHHSFANQHEVVKKVVKTTMSLDRHTLKPLNLDGICNGISSNGMQPLLAIVDDKNNIQIMRGRKLIAEISSYSDQQVTAVRISPCNHYVIYGLSSGIVKKFIVRSKETKDIMDVNSPVMYMSFVNSNMLIVAGENKCLMAYRLTDNGEWEPLMLMRGNTDLGSQELLNDIQGVKKKPQQLSSIDSESSINSREFYFNSVTSKLCKGSSLVDCYWIQGMGLVTIESNATIKLWDENLELDKVLHGKQTAPIQSKDVRLCCSDYKKNILVICDYSNECFQTFEVRHGQMNLIQEYELKKKIYSCALTDDGNILALGLESGDVVLWSVANKRLLEVLKHHSSRVQCCCFSPVPYRRGRPGALSPAGTPGDDEPPLVLVTMTADVVWWDVSYIIRRRLNRNLRTGRTILTPLPSPMEFKNEIQSDDNANKNNYFFNDNLLNPTQMWKANWKHKTYKEGSKRKEILACIKLSGMNAKKICHDEKFSCFVTVDNPGLIYIMTLMGSV-

Monarch geneset OGS2.0

Nucleotide sequence:

Protein sequence: