MonarchBase - Protein-coding gene

DPOGS213478
Transcript	DPOGS213478-TA	5016 bp
Protein	DPOGS213478-PA	1671 aa
Genomic position	DPSCF300100 + 24457-43884
RNAseq coverage	499x (Rank: top 25%)

Annotation
*Heliconius*	HMEL016861	0.0	64.29%
*Bombyx*	BGIBMGA004358-TA	0.0	91.06%
*Drosophila*	Fak56D-PD	5e-121	38.64%
EBI UniRef50	UniRef50_E2AKA8	0.0	54.59%	Focal adhesion kinase 1 n=21 Tax=Metazoa RepID=E2AKA8_CAMFO
NCBI RefSeq	XP_001120873.1	0.0	59.46%	PREDICTED: similar to Focal adhesion kinase 1 (FADK 1) (pp125FAK) [Apis mellifera]
NCBI nr blastp	gi\|350402983	0.0	56.91%	PREDICTED: hypothetical protein LOC100742416 [Bombus impatiens]
NCBI nr blastx	gi\|307176717	0.0	54.59%	Focal adhesion kinase 1 [Camponotus floridanus]

Group
Gene Ontology	GO:0004713	6.2e-113	protein tyrosine kinase activity
	GO:0006468	4.1e-59	protein phosphorylation
	GO:0004672	4.1e-59	protein kinase activity
	GO:0016772	5.1e-50	transferase activity, transferring phosphorus-containing groups
	GO:0005925	3.4e-41	focal adhesion
	GO:0007172	3.4e-41	signal complex assembly
	GO:0004871	3.4e-41	signal transducer activity
	GO:0005524	3.8e-18	ATP binding
	GO:0004674	3.8e-18	protein serine/threonine kinase activity
	GO:0005488	2.4e-07	binding
KEGG pathway	ame:724973	0.0
	K05725 (PTK2, FAK)	maps->	Axon guidance
			Amoebiasis
			Regulation of actin cytoskeleton
			Bacterial invasion of epithelial cells
			Small cell lung cancer
			Chemokine signaling pathway
			Pathways in cancer
			Leukocyte transendothelial migration
			Focal adhesion
			ErbB signaling pathway
			VEGF signaling pathway
InterPro domain	[632-1024] IPR020635	6.2e-113	Tyrosine-protein kinase, catalytic domain
	[863-1024] IPR001245	4.1e-59	Serine-threonine/tyrosine-protein kinase
	[865-1047] IPR011009	5.1e-50	Protein kinase-like domain
	[1377-1508] IPR005189	3.4e-41	Focal adhesion kinase, targeting (FAT) domain
	[339-460] IPR019748	7.8e-37	FERM central domain
	[247-465] IPR019749	9.5e-29	Band 4.1 domain
	[632-1025] IPR002290	3.8e-18	Serine/threonine-protein kinase domain
	[347-455] IPR014352	2.4e-07	FERM/acyl-CoA-binding protein, 3-helical bundle
Orthology group	MCL11430		Multiple-copy universal gene

Nucleotide sequence:

>DPOGS213478-TA
ATGGTTATGGAGTCCGCTCAGCCCGCTGGGCGCTTCTGGCCGTTATCGCCGCGTCTCTGGCGAAGGAGCAACGAGTACACGAAGGTCGTGTTCGAGCCGAGACGACCTCCGGTATCGCCGATCGAAATACGAAAGCACGGGAGGATCGACGAGACGCCCGATCTGTTGCGCTCCAGAAGTTTCATACAGGATAACATGAAAGTGGAGGGCAAGGAATTCGGAGAACTTATGGTTGACAAGCAGAGATGGAGCGTGGATTCAAAGAAACCGCCCGTTAAGGAGGCTAGGAAAGAGGAGGTAGTGAAAATGAGATCAAAGAAACAAAGACAGCCGAGGCCGAACAGCATTCAGCTGCTTTTGTGCCCTTCGAACTCAGGTCATTACAGCAGCAACACTTGGAGATACACGAGGGGCAAGGAATTCGGAGAACTTATGGTTGACAAGCAGAGATGGAGCGTGGATTCAAAGAAACCGCCCGTTAAGGAGGCTAGGAAAGAGGAGGTAGTGAAAATGAGATCAAAGAAACAAAGACAGCCGAGGCCGAACAGCATTCAGCTGCTTTTGTGCCCTTCGAACTCAGGTCATTACAGCAGCAACACTTGGAGATACACGAGGGTCAGATCTAAGAGCCATGAGCCGGAAGGTGGCGGGAGGTGCGAGGGTCCGCTAGCTCGAGCCATGCAGCCTTCACAGGAAAGATCCCCCAAGAGACAGGTCCCAGCGCCCACGCATGGAGCGGCAGCAGACCCGTCCACTTTAAAGGTCCATCTTCCGAACGGCGGCTTCAACGTTGTGAGGGCGTCCCCGGACGAAGATGTTAGATCTGTTCTACGATGTCTGGCGACGAGGCTGGCGACTGGCGACCGCGTGTACGCGTCCTGCTATGCTTTGAGGGCTCGGAGACTAACTACTGGAAAGACCCGTTGGATCCACCAAGACACTCCTGTCTCCGAACTCACCTCTCGCTGGCCGGCCAGTGAGTGGCGGCTCGAGCTGAGGGTTCGCTATCTGCCGGCGAACTTAAGAGACCTCTGCGACTCCGACCGCGTCACCTTCCATTATTACTACGACCAGGTTCGTCATGACTACCTCAACGCTAACCATCCGATGGTCGACCAGGATTTGGCGATTCAAATATGCTGTTTAGAAATAAAATATTTCTGCAAGGACATGCAAATATCTTTGGACAAGAAATCTAATATAGAATATTTGGAGAAAGAATTCGGTCTGCACAAGTTCCTCCCAAAGTCCGTTCTGGAGGCCATCAAACCTAAAGTACTCAAGAAGGCTATACAGCAACAGTTCAAGAAGGTATCAAATCTGAGTGACACTGAGTGTATGTTGAAGTACTTGGAGACGATGCACACGCACTATGGGTACGACCGCGAAACGTTCACGGGCGCTCTTGGTACAGGGTGGGCTATACCGGTGGAACTAGCCATTGGACCTGATATTGATATATCGTACGTGTCCCACAAGGCCGGCGAGCCCCCCACCTACACCAAGATAGCGTCTTTCAGCGACATCATCGCCGTCCAAACACTCAAGTCTAACTGCACCCAGCAGTCACAGTCACAAACCAGCTCCTGCGGCAAGGCTGCCCTTCAGCTCCGTGTGAAGGGCGCGGCGGAAACGTTAACTATAACGTGCAGCAGCGTCGAGGCTGCAGAAAGCTTAGCGGACCTAGTGGATGGTTATTGCCGGCTTGTGACTGACTCGCAGACATCGCTGTGGAACAGAACTACCGAGGTAAGCAGCAGTTCGTCAGAGGGTAAGAGCAGTTCTTTGGAAGGTCACCACACCATGTTGTCGGAGGACTACGCCGAAATCGCGGACGATGACCCCGACTATTCAACGCCGGCTGTTCGAGATTATGAATTGGTTCGTAATCAAATAGAATTGACTGGCATCATTGGAGAGGGACAGTTTGGGGACGTTCATAAAGGCACGTGTAAGGTATCTGGTGCCAATCACCCGTCTCTCCGACGTCAGCTACAGGCCGGTCGAGGTGAGCTGGTTCTCCCCGTCGCTGTGAAGACATGCAAGATGGACGCCGATCTAGACACGGCTGAGAAATTCCTCGAGGAAGCTTATATCATGCAGCAGTTCTCTCACCCCCACATCATCAGTCTGGTGGGAGTGTGTTCAACGCCTCCCATATGGATCGTCATGGAACTGGCCACGTTAGGAGAGATGAGAGCATACCTTCAACAGAACGCACATAGGTTGGAGACGTGTACCCTAGTGCTGTACATCTACCAGCTGTCGACCGCACTCAGTTATTTGGAAAGCAAGAAATTCGTACACAGGGACATAGCTGCTAGGAACGTGCTGGTGTCCACGCCGACCTGTGTTAAGTACGGGATGATAAATACAAGAACTATTCTGCTCATATTGGAACTGATCACACCAGAAGCCTCAGGGTGGAGCCCGGCTGGTGTCAATGAGTTTTTTGTTATATTTATTGTATGGCAGTTGCTATTGCAGCATGAGTTCAACACCGGTTTATTACTGAACAGAGCTGCCTGGATTGCTATGTTTTTATCTGCTGTGCAAATTAAACGTGCTCTTATGTGTGTGTATTATACTCCCAGGTTGGAGACGTGTACCCTAGTGCTGTACATCTACCAGCTGTCGACCGCACTCAGTTATTTGGAAAGCAAGAAATTCGTACACAGGGACATAGCTGCTAGGAACGTGCTGGTGTCCACGCCGACCTGTGTTAAGTTGGCTGACTTCGGTCTTTCAAAAATGGTGGAAGACAAGTCGTACTACAAGGCGTCCCGCGGGAAGTTGCCCATCAAATGGATGGCGCCTGAATCTATTAACTTTAGGAGATTCACTTCCGCTTCCGACGTGTGGATGTTCGGTGTGTGTATGTGGGAGATCCTTATGCTGGGCGTGAAACCGTTCAGTGGCGTCAAAAACAACGACGTGATCGGCAAGCTCGAGAACGGTGAGCGACTGGCGCTGCCGCCTCGCTGCCCGCCACGCCTGTACTCCCTCATGTCCCACTGCTGGGCCTACGAACCCTCGCAGAGACCCACGGCGCACCAGCTCAAAGAAACGCTCTTTGAAATCCTGCAAGAGGAACGGAACACGGCCTGGGACACTATGAGGAGGGAGAACAGACGAGTGGCGGCCGCCTCGTGGGGAGACGACCCCCCGCCCAAACCATCACGGCAACCGCACACACACGCACCAGGAACTGACTCGGGCGGTCCGCAGACGTACATCGTGGCGCAGAGCCCGGCTGTGTTGGCGCAGCTGCTGAGGGAGAACCCCGCGCGCGCCGACCCGCACGCCTACACCACGCCCGCCTCGGTATTCAACACGCTCGCTGTGTTCACCCCCGACTCCGACCCCGACCCCCCCGCCTCCCCCTCCCCCGCCGTTGCCCCTGCCCCCGCTCCCGCCCCCGCGCTCCTCACTAGACCCATCCCCGTGACTCAGCTGCACCGCCTGGACCCACTGGTCCCCGACGACGCCCCCGCAACTCACCAGGGACGGATAGCGGCGCCCGACTCGGTCCGATCGTTGGAGCGCATGCCGCGAGTCCTGGAGAGGGCACCGGTGAGGGTGGGCTCCTTGGAGCGGAACAGTCGTCCGAGCGGGGCTCCCCCGTTGTTCCGCCAGCAGTCGGTGCCGGCGTCTCCGCCGCGCGCGCGGCGCGAGCGCGACGTGGGTCAGTTCTCGGTGCAGGGCTCGCTGAACGCTCAGCTGGCGGCCAGCGTCCTCAACAAGATGAGGCAGCAGCCGGAGCCGCCGCTCGTGGAGGAGATATACGACTTCGGCGGAGATAACGTTAGGAGCTGCGTCGCGATCGCGCAGCGATCGGGCGGCCGCCGGGGCCGTAGGGTGGCGTCACACCTGGCGCCGCCCTATGGCCCCTCGGGCCCCGCGTCCGGGCCTCAATGCGCCGCTCTCGGGCCCCCTGGGCCCCTTATCGCCGCGGACCAGAAGCGACTCTCTAACGTACAAATGGCCCCGGAGGCGGACACCGAGAGGCAAGAGCAAGCGACGCCGGACGTCAAACCCACCAGCCACACACCGACCGCGTCCAACTCATCAGAGACGAGCCCCGCCAGCACAGTGAACACTAAAGACAGACCAGCCAGTGAAGATAAAGGCCGTGTGAAGGAGCCGGTGTACAGCGCAACCACGGCCGTGGTGAGGTGTGTGATGTGCCTGGCGGGTGCCGCCACCAGCACGCCGCGGTCGGCGCCCACCGTGCTCGCAGCTGTGAGGGCGGTGGGTGAAGCTCTAAGGCATTTATGCGCAACCGTCGACAAACTTGTCGCTTTGTACCCGCCCGCAGCACAAAGGGAGGTTGAAATGGCACATCAGGTACTGAGCAAGGACATGGCGGCCCTCGTGGAAGCCATGAGACTCGCCATCCACTACGCGAGGACCACGCTGCAGCAGGATTACACCAAGAGTATGCTCGCCGCCGCGCACGTGCTAGCGATGGACGCCAAAAACCTATTAGACGTAGTGGACTGTATACGCGAGAGACATCCCCACGTGGACTGGCGCTCCGCCCTCCGCGACGTGTCACCCGAGCCCGGGCCTCCGCCCCTCGACAACCAGACGCTCAGCTCGCAGAACCAAGTGTTCGCGCCCCAATGCCAGACCCTGACTCCTCAGAACCCGGTCCTCAGCACGCAGTCCTCACTACAAGAGCCGATCAAACCCGACTTTAAAGTCAACCAGCCGGTGACGGCAGTGACGACCGCCATACACGTCGACCAGCACAAGGAACACAACAGTCTGCCGGTCACCTCCAACAGAGTGTCCACTCTCATCCACAACTTCAACTTCGGGAACGTCAAAGACCAGCACATATACGGCAACGAGACGCAGTTCCAGCACTCGCAGTCCTGTGACGATTCCAAGCTAGACGGCGCGCCCTACGAGACGGCCAGGAACAGGGTCCAAGCGGCGACCAAGGACACCCCGGCTATATACTCGGTTTCCAAAAAAATGCTGCCCTTGGAGCACAGCGACCAGGGCTGA

Protein sequence:

>DPOGS213478-PA
MVMESAQPAGRFWPLSPRLWRRSNEYTKVVFEPRRPPVSPIEIRKHGRIDETPDLLRSRSFIQDNMKVEGKEFGELMVDKQRWSVDSKKPPVKEARKEEVVKMRSKKQRQPRPNSIQLLLCPSNSGHYSSNTWRYTRGKEFGELMVDKQRWSVDSKKPPVKEARKEEVVKMRSKKQRQPRPNSIQLLLCPSNSGHYSSNTWRYTRVRSKSHEPEGGGRCEGPLARAMQPSQERSPKRQVPAPTHGAAADPSTLKVHLPNGGFNVVRASPDEDVRSVLRCLATRLATGDRVYASCYALRARRLTTGKTRWIHQDTPVSELTSRWPASEWRLELRVRYLPANLRDLCDSDRVTFHYYYDQVRHDYLNANHPMVDQDLAIQICCLEIKYFCKDMQISLDKKSNIEYLEKEFGLHKFLPKSVLEAIKPKVLKKAIQQQFKKVSNLSDTECMLKYLETMHTHYGYDRETFTGALGTGWAIPVELAIGPDIDISYVSHKAGEPPTYTKIASFSDIIAVQTLKSNCTQQSQSQTSSCGKAALQLRVKGAAETLTITCSSVEAAESLADLVDGYCRLVTDSQTSLWNRTTEVSSSSSEGKSSSLEGHHTMLSEDYAEIADDDPDYSTPAVRDYELVRNQIELTGIIGEGQFGDVHKGTCKVSGANHPSLRRQLQAGRGELVLPVAVKTCKMDADLDTAEKFLEEAYIMQQFSHPHIISLVGVCSTPPIWIVMELATLGEMRAYLQQNAHRLETCTLVLYIYQLSTALSYLESKKFVHRDIAARNVLVSTPTCVKYGMINTRTILLILELITPEASGWSPAGVNEFFVIFIVWQLLLQHEFNTGLLLNRAAWIAMFLSAVQIKRALMCVYYTPRLETCTLVLYIYQLSTALSYLESKKFVHRDIAARNVLVSTPTCVKLADFGLSKMVEDKSYYKASRGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMLGVKPFSGVKNNDVIGKLENGERLALPPRCPPRLYSLMSHCWAYEPSQRPTAHQLKETLFEILQEERNTAWDTMRRENRRVAAASWGDDPPPKPSRQPHTHAPGTDSGGPQTYIVAQSPAVLAQLLRENPARADPHAYTTPASVFNTLAVFTPDSDPDPPASPSPAVAPAPAPAPALLTRPIPVTQLHRLDPLVPDDAPATHQGRIAAPDSVRSLERMPRVLERAPVRVGSLERNSRPSGAPPLFRQQSVPASPPRARRERDVGQFSVQGSLNAQLAASVLNKMRQQPEPPLVEEIYDFGGDNVRSCVAIAQRSGGRRGRRVASHLAPPYGPSGPASGPQCAALGPPGPLIAADQKRLSNVQMAPEADTERQEQATPDVKPTSHTPTASNSSETSPASTVNTKDRPASEDKGRVKEPVYSATTAVVRCVMCLAGAATSTPRSAPTVLAAVRAVGEALRHLCATVDKLVALYPPAAQREVEMAHQVLSKDMAALVEAMRLAIHYARTTLQQDYTKSMLAAAHVLAMDAKNLLDVVDCIRERHPHVDWRSALRDVSPEPGPPPLDNQTLSSQNQVFAPQCQTLTPQNPVLSTQSSLQEPIKPDFKVNQPVTAVTTAIHVDQHKEHNSLPVTSNRVSTLIHNFNFGNVKDQHIYGNETQFQHSQSCDDSKLDGAPYETARNRVQAATKDTPAIYSVSKKMLPLEHSDQG-

Monarch geneset OGS2.0

Nucleotide sequence:

Protein sequence: